DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Db and serpine3

DIOPT Version :9

Sequence 1:	NP_001356884.1	Gene:	Spn28Db / 326261	FlyBaseID:	FBgn0053121	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_001116709.1	Gene:	serpine3 / 556612	ZFINID:	ZDB-GENE-050309-223	Length:	417	Species:	Danio rerio

Alignment Length:	406	Identity:	101/406 - (24%)
Similarity:	186/406 - (45%)	Gaps:	66/406 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 IATSVLG--------KFKLNLLE-LVMDKAESNFIASPLCIEIGISMILMGAKGTTAEELRSVLD 70
            :|.|||.        :|.::|.: |...:.:||.|.||..:.:.:.::.:||:|.|..:|...|.
Zfish    21 VANSVLSSSFSDLHTQFGISLYQTLTETENKSNLIVSPASVSLCLGLLQLGARGNTLVQLEGTLG 85

  Fly    71 LPVD---VTEMAKKYERIMSNFQKHNGLRFTNWLYVNETYEVRQDY--------NTLMKST---- 120
            ..|:   |..:..:.:..::|..:...|:..|.|::....::..::        ||.:.|.
Zfish    86 YDVNDVRVQNILSRPQGDLANSSEGLRLQLANALFIQTGVKLLPEFTQHALGWGNTSLLSVNFSN 150

  Fly   121 -------------FMAEGKDPLSQRKASNSISFSIHRKSHKGMRTISNDHNLQINESAVLVNTVY 172
                         :.::..|.|..|:       .:|..|.:.......||.|.:    .||:|:.
Zfish   151 PNHTHSRLQQWAHYQSKADDHLQTRE-------ELHHSSGEEEEATRQDHLLYM----ALVSTLV 204

  Fly   173 YSGAWKTRFSKKDTKLKVFHGDHNKKVYVRMM-----SHVGRFRIADHSYGQIIEMPFDNSDLSM 232
            :.|||:.:|...:|:...|.......|.|.||     .::|.||:.......::|:|:.:..|.:
Zfish   205 FHGAWQKQFLFTETQNLPFTFSDGSTVKVPMMYQSSEVNIGHFRLPSEQEYTVLELPYLDHSLRL 269

  Fly   233 IIGLPL-HNTYLSSIEKILRTLSESLVENNVH-----VELPKFKIKYQTELVESLKKLGIHLIFS 291
            ::.||. ..|.||.:||.:...:..|.:..:.     :.||:||::.:..|...|:.||:..|||
Zfish   270 LVALPSDRKTPLSQLEKQITARAVGLWDTGLRRTKMDIFLPRFKMQSKINLKPVLQSLGVSDIFS 334

  Fly   292 -NTSDLSGLLTNGTGAKINHVVHKSFIEINERGASTGEASDHAESIQKKTRASTSFKVNRPFVFL 355
             :.:|..| :::..|..::...|::.||:.|.|  |..||..|..:.|::| |..||.:|||:|:
Zfish   335 PSAADFRG-ISDTDGIFVSEAFHEARIEVTEAG--TKAASATAMVLLKRSR-SAVFKADRPFLFI 395

  Fly   356 IRDKHT--VYFRGRVV 369
            :|...|  :.|.||||
Zfish   396 LRQISTGSLLFIGRVV 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Db	NP_001356884.1	SERPIN	22..368	CDD:238101	94/388 (24%)
serpine3	NP_001116709.1	Serpin	35..413	CDD:278507	97/392 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.110