Protein Alignment Spn28Db and SERPINB5

DIOPT Version :9

• Sequence 1: NP_001356884.1
• Gene: Spn28Db / 326261
• FlyBaseID: FBgn0053121
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_002630.2
• Gene: SERPINB5 / 5268
• HGNCID: 8949
• Length: 375
• Species: Homo sapiens
• Alignment Length: 382
• Identity: 110/382 - (28%)
• Similarity: 182/382 - (47%)
• Gaps: 41/382 - (10%)

  Fly    13 LLIATSVLGKFKLNLLELVMDKAE-SNFIASPLCIEIGISMILMGAKGTTAEELRSVLDLPVDVT 76
            |.:|.|.   |.::|.:.:.:|.. .|.:.||:|:...:|:..:||||.||.|:..||... :|.
Human     4 LQLANSA---FAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFE-NVK 64

  Fly    77 EMAKKYERIMSNFQKHN---GLRFTNWLYVNETYEVRQDYNTLMKSTFMAE-----GKDPLSQRK 133
            ::...::.:.|:..|.:   .|:....|||:::..:..::.:..|..:..|     .||.|.:.|
Human    65 DVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLEETK 129

  Fly   134 ASNSISFSIHRKSHKGMRTISNDHNLQINESAVLVNTVYYSGAWKTRFSKKDTKLKVFHGDHNKK 198
              ..|:.||...:......|..|:::......::||..|:.|.|..:||:.:||...|..:....
Human   130 --GQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECPFRVNKTDT 192

  Fly   199 VYVRMMSHVGRFRIA--DHSYGQIIEMPFDNSDLSMIIGLPL----HNTYLSSIEKILRTLSESL 257
            ..|:||:....|.:.  |....:|||:||.|..|||.|.||.    .:|.|..|||.|.  ||||
Human   193 KPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDESTGLEKIEKQLN--SESL 255

  Fly   258 ---------VENNVHVELPKFKIKYQTELVESLKKLGIHLIFS-NTSDLSGLLTNGTGAKINHVV 312
                     ....|.:.:||||::...:....|:.||:..||| :|||.|| ::...|..:::|:
Human   256 SQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSDFSG-MSETKGVALSNVI 319

  Fly   313 HKSFIEINERGASTGEASDHAESIQKKTRASTSFKVNRPFVFLIRDKHT--VYFRGR 367
            ||..:||.|.|..:.|... |..:|.|    .....:.||:::||...|  :.|.|:
Human   320 HKVCLEITEDGGDSIEVPG-ARILQHK----DELNADHPFIYIIRHNKTRNIIFFGK 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Db	NP_001356884.1	SERPIN	22..368	CDD:238101	107/373 (29%)
SERPINB5	NP_002630.2	maspin_like	4..375	CDD:239012	110/382 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.930