Protein Alignment Spn28Db and SERPINA1

DIOPT Version :9

• Sequence 1: NP_001356884.1
• Gene: Spn28Db / 326261
• FlyBaseID: FBgn0053121
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_000286.3
• Gene: SERPINA1 / 5265
• HGNCID: 8941
• Length: 418
• Species: Homo sapiens
• Alignment Length: 402
• Identity: 103/402 - (25%)
• Similarity: 170/402 - (42%)
• Gaps: 73/402 - (18%)

  Fly     5 NKIKYLVLLLIATSVLGKFKLNLL-ELVMDKAESNFIASPLCIEIGISMILMGAKGTTAEELRSV 68
            |||         |..|.:|..:|. :|......:|...||:.|....:|:.:|.|..|.:|:...
Human    48 NKI---------TPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEG 103

  Fly    69 LDLPVDVTEMAKKYERIMSNFQKHNG----LRFTNWLYVNETYEVRQDYNTLMKST----FMAEG 125
            |:.  ::||:.:.        |.|.|    ||..|           |..:.|..:|    |::||
Human   104 LNF--NLTEIPEA--------QIHEGFQELLRTLN-----------QPDSQLQLTTGNGLFLSEG 147

  Fly   126 KDPLSQ-----RKASNSISFSIHRKSHKGMRTISNDH--------------NLQINESAVLVNTV 171
            ...:.:     :|..:|.:|:::....:..:...||:              .|..:....|||.:
Human   148 LKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYI 212

  Fly   172 YYSGAWKTRFSKKDTKLKVFHGDHNKKVYVRMMSHVGRFRIADHS---YGQIIEMPFDNSDLSMI 233
            ::.|.|:..|..|||:.:.||.|....|.|.||..:|.|.| .|.   ...::.|.: ..:.:.|
Human   213 FFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNI-QHCKKLSSWVLLMKY-LGNATAI 275

  Fly   234 IGLPLHNTYLSSIEKILRTLSESLVEN----NVHVELPKFKIKYQTELVESLKKLGIHLIFSNTS 294
            ..||..........::...:....:||    :..:.|||..|....:|...|.:|||..:|||.:
Human   276 FFLPDEGKLQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGA 340

  Fly   295 DLSGLLTNGTGAKINHVVHKSFIEINERGASTGEASDHAESIQKKTRASTSFKVNRPFVFLIRDK 359
            |||| :|.....|::..|||:.:.|:|:|.....|. ..|:|.........|  |:|||||:.::
Human   341 DLSG-VTEEAPLKLSKAVHKAVLTIDEKGTEAAGAM-FLEAIPMSIPPEVKF--NKPFVFLMIEQ 401

  Fly   360 HT--VYFRGRVV 369
            :|  ..|.|:||
Human   402 NTKSPLFMGKVV 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Db	NP_001356884.1	SERPIN	22..368	CDD:238101	96/382 (25%)
SERPINA1	NP_000286.3	alpha-1-antitrypsin_like	55..412	CDD:239011	96/383 (25%)
		RCL	368..392		5/26 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010