Protein Alignment Spn28Db and SERPINA5

DIOPT Version :9

• Sequence 1: NP_001356884.1
• Gene: Spn28Db / 326261
• FlyBaseID: FBgn0053121
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_000615.3
• Gene: SERPINA5 / 5104
• HGNCID: 8723
• Length: 406
• Species: Homo sapiens
• Alignment Length: 374
• Identity: 89/374 - (23%)
• Similarity: 179/374 - (47%)
• Gaps: 26/374 - (6%)

  Fly    15 IATSVLGKFKLNLLELVMDKAESNFI-ASPLCIEIGISMILMGAKGTTAEELRSVLDLPVDVT-- 76
            :|.|....|..:|...:...|.|..| .||:.|.:.::|:.:||..:|..::...|.|.:..:
Human    40 VAPSSRRDFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSE 104

  Fly    77 -EMAKKYERIMSNF-QKHNGLRFT--NWLYVNETYEVRQDYNTLMKSTFMAEG-----KDPLSQR 132
             |:.:.:::::... |..:|.:.:  |.|:.:...:::..:.:.||:.::|:.     :|.....
Human   105 KELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAM 169

  Fly   133 KASNSISFSIHRKSHKGMRTISNDHNLQINESAVLVNTVYYSGAWKTRFSKKDTKLKVFHGDHNK 197
            |..|...    .|..|| :.:....||..|...::||.:::...|:|.|:.|.|:.:.|:.....
Human   170 KQINDYV----AKQTKG-KIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSET 229

  Fly   198 KVYVRMMSHVGRFR-IADHSYG-QIIEMPFDNSDLSMIIGLP----LHNTYLSSIEKILRTLSES 256
            .|.|.|||...::. :.|.:.. :::.:|:..:..::.| ||    :........||.||...:.
Human   230 VVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFI-LPSEGKMQQVENGLSEKTLRKWLKM 293

  Fly   257 LVENNVHVELPKFKIKYQTELVESLKKLGIHLIFSNTSDLSGLLTNGTGAKINHVVHKSFIEINE 321
            ..:..:.:.||||.|:...:|.:.|..|||..:|::.:|||| ::|.:..:::.:|||:.:|::|
Human   294 FKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSG-ISNHSNIQVSEMVHKAVVEVDE 357

  Fly   322 RGASTGEASDHAESIQKKTRASTSFKVNRPFVFLIRDKHTVYFRGRVVR 370
            .|.....|:....:.:.....|.....||||:..|.| :.:.|.|:|.|
Human   358 SGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVD-NNILFLGKVNR 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Db	NP_001356884.1	SERPIN	22..368	CDD:238101	85/363 (23%)
SERPINA5	NP_000615.3	alpha-1-antitrypsin_like	44..403	CDD:239011	85/366 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010