Protein Alignment Spn28Db and SERPINE1

DIOPT Version :9

• Sequence 1: NP_001356884.1
• Gene: Spn28Db / 326261
• FlyBaseID: FBgn0053121
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_001373389.1
• Gene: SERPINE1 / 5054
• HGNCID: 8583
• Length: 492
• Species: Homo sapiens
• Alignment Length: 360
• Identity: 90/360 - (25%)
• Similarity: 155/360 - (43%)
• Gaps: 55/360 - (15%)

  Fly    36 ESNFIASPLCIEIGISMILMGAKGTTAEELRSVLDLPVDVTEMAKK----YERIMSNFQKHNGLR 96
            :.|.:.||..:...::|:.:...|.|.:::::.:...:|...||..    |:.:|..:.| :.:.
Human    52 DRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNK-DEIS 115

  Fly    97 FTNWLYVNETYEVRQDYNTLMKSTFMAEGKDPLSQRKASNSISFS-IHR---------KSH-KGM 150
            .|:.::|....::.|.:.......|          |.....:.|| :.|         |:| |||
Human   116 TTDAIFVQRDLKLVQGFMPHFFRLF----------RSTVKQVDFSEVERARFIINDWVKTHTKGM 170

  Fly   151 RTISNDHNLQINESA-------VLVNTVYYSGAWKTRFSKKDTKLKVFHGDHNKKVYVRMMSHVG 208
              |||    .:.:.|       ||||.:|::|.|||.|....|..::||......|.|.||:...
Human   171 --ISN----LLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTN 229

  Fly   209 RFRIA-----DHSYGQIIEMPFDNSDLSMIIGLPLHNTY-LSSIEKILRTLSESLVENNVH---- 263
            :|...     |..|..|:|:|:....|||.|..|..... ||::..||.....|..:.|:.
Human   230 KFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPR 294

  Fly   264 -VELPKFKIKYQTELVESLKKLGIHLIFSN-TSDLSGLLTNGTGAKINHVVHKSFIEINERGAST 326
             :.||||.::.:.:|.:.|:.||:..:|.. .:|.:. |::.....:...:.|..||:||.|.
Human   295 LLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTS-LSDQEPLHVAQALQKVKIEVNESGT-- 356

  Fly   327 GEASDHAESIQKKTRASTSFKVNRPFVFLIRDKHT 361
             .||.....|.....|.....::|||:|::|...|
Human   357 -VASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPT 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Db	NP_001356884.1	SERPIN	22..368	CDD:238101	90/360 (25%)
SERPINE1	NP_001373389.1	serpinE1_PAI-1	29..393	CDD:381007	90/360 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.020