DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Db and Spn28Da

DIOPT Version :9

Sequence 1:	NP_001356884.1	Gene:	Spn28Db / 326261	FlyBaseID:	FBgn0053121	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_001036345.1	Gene:	Spn28Da / 34082	FlyBaseID:	FBgn0051902	Length:	384	Species:	Drosophila melanogaster

Alignment Length:	378	Identity:	166/378 - (43%)
Similarity:	238/378 - (62%)	Gaps:	23/378 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 IKYLVLLLIATSVLGKFKLNLL-ELVMDKAESNFIASPLCIEIGISMILMGAKGTTAEELRSVLD 70
            :|||..:|:.|||||:|...|. ..:.|..:.|.||||||:|||:|||||||.|.||.|||:.|:
  Fly     1 MKYLCWILVTTSVLGQFTKQLYRSFLQDNKQYNIIASPLCVEIGMSMILMGADGNTANELRTALN 65

  Fly    71 LPVDVTEMAKKYERIMSNFQKHNG---LRFTNWLYVNETYEVRQDYNTLMKSTFMAEGKD-PLSQ 131
            ||.|...:|..|:::::..::...   |...|.|:||||..|.:.||.|:...|.||.:. .|:.
  Fly    66 LPEDKKNVATIYDKLLTKLERGKKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAEAEAIKLAD 130

  Fly   132 R-KASNSISFSIHRKSHKGMRTISNDHNLQINESAVLVNTVYYSGAWKTRFSKKDTKLKVFHGDH 195
            | ||:.:|:..:..::...::.|....:|..:||||::|..::.|.|||||.|.:||.|||:...
  Fly   131 RLKAAWAINDWVLDQTLDNVKDIIIPSDLTPDESAVMINAAFFKGYWKTRFDKMNTKPKVFYVSK 195

  Fly   196 NKKVYVRMMSHVGRFRIADHSYGQIIEMPFDNSDLSMIIGLPLHNTYLSSIEKILRTLSE-SLVE 259
            :.:|.|.|||.||||::...:..||||:||..|:|||:|.||..|..|:..|..:.:..: .|.|
  Fly   196 SYQVNVNMMSQVGRFKMRTSTIDQIIELPFAYSNLSMVIVLPKDNGSLTQAEATIESYPQIVLTE 260

  Fly   260 NNVHVELPKFKIKYQTELVESLKKLGIHLIFSNTSDLSGLLTNGTGAKINHVVHKSFIEINERGA 324
            .:|||:||||||.::.||||:||.:||..:|:::||:|.|| |.:|.:|:.||||:||||:|.|.
  Fly   261 MDVHVQLPKFKIDFRMELVETLKSMGIQDLFNSSSDISVLL-NQSGTRISQVVHKAFIEIDEEGG 324

  Fly   325 STGEA--------SDHAESIQKKTRASTSFKVNRPFVFLIRDKHTVYFRGRVV 369
            |.|.|        ||:|.|:       .:|.||.||||:|||...:|||||||
  Fly   325 SAGSASASPIRGLSDYATSV-------VTFTVNSPFVFMIRDDDNIYFRGRVV 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Db	NP_001356884.1	SERPIN	22..368	CDD:238101	154/360 (43%)
Spn28Da	NP_001036345.1	SERPIN	16..369	CDD:238101	154/360 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468697
Domainoid	1	1.000	172	1.000	Domainoid score	I1138
eggNOG	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H76659
Inparanoid	1	1.050	172	1.000	Inparanoid score	I1521
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D140751at6656
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	P	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.900