DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Db and LOC299282

DIOPT Version :9

Sequence 1:	NP_001356884.1	Gene:	Spn28Db / 326261	FlyBaseID:	FBgn0053121	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_001376144.2	Gene:	LOC299282 / 299282	RGDID:	3745	Length:	413	Species:	Rattus norvegicus

Alignment Length:	411	Identity:	104/411 - (25%)
Similarity:	178/411 - (43%)	Gaps:	77/411 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 QGNNKIKYLVLLLIATSVLGKFKLNLL-ELVMDKAESNFIASPLCIEIGISMILMGAKGTTAEE- 64
            :.:.|.:.|..|.:|:|.. .|.|:|. :|.:...:.|.:.|||.|...::::.:|||.:|.||
  Rat    32 EDHGKGRQLHSLTLASSNT-DFALSLYKKLALRNPDKNVVFSPLSISAALTILSLGAKDSTMEEI 95

  Fly    65 ----------------------LRSVLDLPVDVTEM-------AKKYERIMSNFQKHNGLRFTNW 100
                                  |...|..|.|..|:       ..|.:.|:|.||:.     |..
  Rat    96 LEGLKFNLTEITEEEIHQGFGHLLQRLSQPEDQVEINTGSALFIDKEQPILSEFQEK-----TRA 155

  Fly   101 LYVNETYEVRQDYNTLMKSTFMAEGKDPLSQRKASNSISFSIHRKSHKGMRTISNDHNLQINESA 165
            ||..|              .|:|:.|.|...:|..|..   :..::...:..:.:|  |:...|.
  Rat   156 LYQAE--------------AFIADFKQPNEAKKLINDY---VSNQTQGKIAELFSD--LEERTSM 201

  Fly   166 VLVNTVYYSGAWKTRFSKKDTKLKVFHGDHNKKVYVRMM--SHVGRFRIADHSYG-QIIEMPFDN 227
            ||||.:.:.|.||..|:..||....|:.|..:.|.|.||  ..|....:.|.... .::|:.:..
  Rat   202 VLVNYLLFKGKWKVPFNPNDTFESEFYLDEKRSVKVPMMKIKEVTTPYVRDEELSCSVLELKYTG 266

  Fly   228 SDLSMIIGLP----LHNTYLSSIEKILRTLSESLVENNVH-VELPKFKIKYQTELVESLKKLGIH 287
            :..::.| ||    :.....|...:.|:...:||:...:: :.:|||.|.....|.|.|.:|||.
  Rat   267 NASALFI-LPDQGKMQQVESSLQPETLKKWKDSLIPRIINDLRMPKFSISTDYSLKEVLPELGIK 330

  Fly   288 LIFSNTSDLSGLLTNGTGAK---INHVVHKSFIEINERGASTGEASDHAESIQKKTRASTSFKVN 349
            .:||..:|||.:    ||.|   ::.||||:.::::|.|.....|:..|..|:::.|   :...|
  Rat   331 KVFSQQADLSRI----TGTKDLYVSQVVHKAVLDVDETGTEATAATGVATVIRRQPR---TLNFN 388

  Fly   350 RPFVFLI--RDKHTVYFRGRV 368
            |||:.:|  .|..::.|..::
  Rat   389 RPFMVVITDMDSQSILFVAKI 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Db	NP_001356884.1	SERPIN	22..368	CDD:238101	99/389 (25%)
LOC299282	NP_001376144.2	serpinA3_A1AC	36..413	CDD:381019	104/407 (26%)
LOC299282	NP_001376144.2	RCL	365..389		5/26 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010