DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Db and Serping1

DIOPT Version :9

Sequence 1:	NP_001356884.1	Gene:	Spn28Db / 326261	FlyBaseID:	FBgn0053121	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_954524.1	Gene:	Serping1 / 295703	RGDID:	735225	Length:	504	Species:	Rattus norvegicus

Alignment Length:	369	Identity:	84/369 - (22%)
Similarity:	160/369 - (43%)	Gaps:	70/369 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 KAESNFIASPLCIEIGISMILMGAKGTTAEELRSVLDLPVDVTEMAKKYERIMSNFQKHNGLRFT 98
            |||:|...||..|...::.:|:||..:|...|..:|..|.|...:.:..:...|     .|:...
  Rat   167 KAETNMAFSPFSIASLLTQVLLGAGDSTKSNLEDILSYPKDFACVHQTLKAFSS-----KGVTSV 226

  Fly    99 NWLYVNETYEVRQDYNTLMKSTFMAE----GKDPLSQRKASNS-ISFSIHRKSHKGMRTISNDHN 158
            :.::.:....:|..|.....|.:.:.    |.|..:..|..|: ::.:.:.|.::.:.::.:|..
  Rat   227 SQIFHSPDLAIRDTYVNASLSLYGSSPRVLGPDGDANLKLINTWVAENTNHKINELLDSLPSDTR 291

  Fly   159 LQINESAVLVNTVYYSGAWKTRFSKKDTKLKVFHGDHNKKVYVRMMS----------------HV 207
            |      ||:|.||.|..||..|.:|.......:  .|..:.|.|:|                .|
  Rat   292 L------VLLNAVYLSAKWKKTFEQKKMMASFLY--KNSMIKVPMLSSKKYPLALFNDQTLKAKV 348

  Fly   208 GRFRIADHSYGQIIEMPFDNSDLSMIIGLPLHNTY-LSSIEKILR-TLSESLVE-------NNVH 263
            |:.::              :.:||.:|.:|...|: |..:||.|. |:.:::::       ...:
  Rat   349 GQLQL--------------SHNLSFVIMVPQSPTHQLEDMEKALNPTVFKAILKKLELSKFQPTY 399

  Fly   264 VELPKFKIKYQTELVESLKKLGIHLIFSNTSDLS--GLLTNGTGAKINHVVHKSFIEINERGAST 326
            |.:|:.|:|...:::..::||.   .|..|.||:  | ||.....:::.:.|::.:|:.|.|...
  Rat   400 VMMPRIKVKSSQDMLSIMEKLE---FFDFTYDLNLCG-LTEDPDLQVSSMKHETVLELTETGVEA 460

  Fly   327 GEASDHAESIQKKTRASTSFKVNRPFVFLIRDKHTVY--FRGRV 368
            ..||..:.:     |....|:|.:||:||:.|:...:  |.|||
  Rat   461 AAASTISVA-----RNLLIFEVQQPFLFLLWDQRHKFPVFMGRV 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Db	NP_001356884.1	SERPIN	22..368	CDD:238101	82/367 (22%)
Serping1	NP_954524.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	23..75
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	94..132
		SERPIN	150..499	CDD:294093	82/367 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100