DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Db and Serpinb6a

DIOPT Version :9

Sequence 1:	NP_001356884.1	Gene:	Spn28Db / 326261	FlyBaseID:	FBgn0053121	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	XP_006253933.1	Gene:	Serpinb6a / 291085	RGDID:	735108	Length:	400	Species:	Rattus norvegicus

Alignment Length:	380	Identity:	99/380 - (26%)
Similarity:	182/380 - (47%)	Gaps:	46/380 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 GKFKLNLLELVMDKAESNFIASPLCIEIGISMILMGAKGTTAEELRSVLDLPV-------DVTEM 78
            |.|.|.||:.:.:.:.:|...||:.|...::|:.|||||.||.::...|.|..       ||.:
  Rat    30 GIFALKLLKTLSEDSSNNIFLSPISISAALTMVFMGAKGMTASQMVQTLSLDKCSGNGGGDVHQ- 93

  Fly    79 AKKYERIMSNFQKHNG---LRFTNWLYVNETYEVRQDYNTLMKSTFMAE-------GKDPLSQRK 133
              .::.:::...|...   |:..|.|:..:|.::...:....:..:.||       |....|:::
  Rat    94 --GFQSLLAEVNKTGTQYLLKTANRLFGEKTCDILASFKDACRKFYEAEMEELDFKGDTEQSRQR 156

  Fly   134 ASNSISFSIHRKSHKGMRTISNDHNLQINESAVLVNTVYYSGAWKTRFSKKDTKLKVFHGDHNKK 198
                |:..:.:|:...::.:.....:..:...||||.:|:.|.|..:|:|:.|:.|.|.....::
  Rat   157 ----INTWVAKKTEDKIKELLAPGIVDPDTVLVLVNAIYFKGNWDKQFNKEHTREKPFKVSKTEE 217

  Fly   199 VYVRMMSHVGRFRIA--DHSYGQIIEMPFDNSDLSMIIGLPLHNTYLSSIEKILR-------TLS 254
            ..|:||.....|::.  ...:.:|:.:|:..::|:|||.||..:..|.::||.|.       |..
  Rat   218 KPVQMMFMKSTFKMTYIGEIFTKILLLPYAGNELNMIIMLPDEHIELKTVEKELTYEKFIEWTRL 282

  Fly   255 ESLVENNVHVELPKFKIKYQTELVESLKKLGIHLIF-SNTSDLSGLLTNGTGAKINHVVHKSFIE 318
            :.|.|..|.|.||:||::...::...|.|||:...| ...:|.||:.:. .|..::.|:||:|:|
  Rat   283 DMLDEEEVEVFLPRFKLEENYDMKVVLGKLGMTDAFMEGRADFSGIASK-QGLFLSKVIHKAFVE 346

  Fly   319 INERG----ASTGEASDHAESIQKKTRASTSFKVNRPFVFLIRDKHT--VYFRGR 367
            :||.|    |:||     :....:..|.:..|..:.||:|.|:...|  :.|.||
  Rat   347 VNEEGTEAVAATG-----STITMRCLRFTPRFLADHPFLFFIQHVKTKGILFCGR 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Db	NP_001356884.1	SERPIN	22..368	CDD:238101	98/379 (26%)
Serpinb6a	XP_006253933.1	SERPIN	25..400	CDD:294093	99/380 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.830