Protein Alignment Spn28Db and SERPINB1

DIOPT Version :9

• Sequence 1: NP_001356884.1
• Gene: Spn28Db / 326261
• FlyBaseID: FBgn0053121
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_109591.1
• Gene: SERPINB1 / 1992
• HGNCID: 3311
• Length: 379
• Species: Homo sapiens
• Alignment Length: 393
• Identity: 103/393 - (26%)
• Similarity: 173/393 - (44%)
• Gaps: 74/393 - (18%)

  Fly    22 KFKLNL-LELVMDKAESNFIASPLCIEIGISMILMGAKGTTAEELRSVLDLPVDVTEMAKKYERI 85
            :|.|:| |.|..:....|...||..|...::|:.:|.:|.||.:|........ |.|:..:::.:
Human    10 RFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFNT-VEEVHSRFQSL 73

  Fly    86 MSNFQKHNG---LRFTNWLYVNETYEVRQDYNTLMKSTFMAEGKDPLSQRKASNSISFSIHRKSH 147
            .::..|...   |:..|.||..:||....::....:.|:.|:            ..|......|.
Human    74 NADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGAD------------LASVDFQHASE 126

  Fly   148 KGMRTISN-------------------DHNLQINESAVLVNTVYYSGAWKTRFSKKDTKLKVFHG 193
            ...:||:.                   |:..::    ||||.:|:.|.||.:|.|:.|....|..
Human   127 DARKTINQWVKGQTEGKIPELLASGMVDNMTKL----VLVNAIYFKGNWKDKFMKEATTNAPFRL 187

  Fly   194 DHNKKVYVRMMSHVGRFRIADHSYG-------QIIEMPFDNSDLSMIIGLP----LHNTYLSSIE 247
            :...:..|:||....:|     :||       :::|:|:...:|||:|.||    ..:|.|..||
Human   188 NKKDRKTVKMMYQKKKF-----AYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDESTGLKKIE 247

  Fly   248 KILR-------TLSESLVENNVHVELPKFKIKYQTELVESLKKLGIHLIF-SNTSDLSGLLTNGT 304
            :.|.       |..|:|....|:|.||:||::....|...|.:||:..:| |:.:||||:    :
Human   248 EQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSKADLSGM----S 308

  Fly   305 GAK---INHVVHKSFIEINERGASTGEASDHAESIQKKTRASTSFKVNRPFVFLIR--DKHTVYF 364
            ||:   |:.:|||||:|:||.|.....|:....:. .......:|..:.||:|.||  ...::.|
Human   309 GARDIFISKIVHKSFVEVNEEGTEAAAATAGIATF-CMLMPEENFTADHPFLFFIRHNSSGSILF 372

  Fly   365 RGR 367
            .||
Human   373 LGR 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Db	NP_001356884.1	SERPIN	22..368	CDD:238101	103/393 (26%)
SERPINB1	NP_109591.1	SERPIN	4..379	CDD:294093	103/393 (26%)
		CARD-binding motif (CBM). /evidence=ECO:0000269|PubMed:30692621	351..379		9/25 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.930