DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Db and Serpina3c

DIOPT Version :9

Sequence 1:	NP_001356884.1	Gene:	Spn28Db / 326261	FlyBaseID:	FBgn0053121	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	XP_011242304.1	Gene:	Serpina3c / 16625	MGIID:	102848	Length:	436	Species:	Mus musculus

Alignment Length:	385	Identity:	102/385 - (26%)
Similarity:	175/385 - (45%)	Gaps:	48/385 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LIATSVLGKFKLNLL-ELVMDKAESNFIASPLCIEIGISMILMGAKGTTAEELRSVLDLPVDVTE 77
            |...|:...|..:|. :|.:...::|.:.|||.|...::::.:||||.|.||:...|:..:..|.
Mouse    64 LTLASINTDFAFSLYKKLALKNPDTNIVFSPLSISAALAIVSLGAKGNTLEEILEGLNFNLTETP 128

  Fly    78 MAKKYERIMSNFQK--HNG----LRFTNWLYVNETYEVRQDYNTLMKSTFMAEG-----KDPLSQ 131
            .|..::......|:  |.|    :...:.|:|.:..::..::....::.:.||.     :.||..
Mouse   129 EADIHQGFGHLLQRLSHPGEQVQISTGSALFVEKHLQILAEFQEKARALYQAEAFTADFQQPLEA 193

  Fly   132 RKASNSISFSIHRKSHKGMRTISNDHNLQINESAVLVNTVYYSGAWKTRFSKKDTKLKVFHGDHN 196
            .|..|....:..::..||:  ||   :|..:...||||.:|:.|.||..|:.:||....|:.|..
Mouse   194 TKLINDYVSNQTQRKIKGL--IS---DLDTDTLMVLVNYIYFKGKWKMPFNPRDTFESEFYLDVK 253

  Fly   197 KKVYVRMMS----HVGRFRIADHSYGQIIEMPFDNSDLSMIIGLP----LHNTYLSSIEKILRTL 253
            :.|.|.||.    ....||..:.|. .::|:.:..:..::.| ||    :.....|...:.||..
Mouse   254 RSVKVPMMKIKTLTTPYFRDEELSC-TVVELKYKGNASALFI-LPDQGRMQQVEASLQPETLRKW 316

  Fly   254 SESLVENNV-HVELPKFKIKYQTELVESLKKLGIHLIFSNTSDLSGLLTNGTGAK---INHVVHK 314
            ..||....: .:.||||.|.....|...|.:|||..|||..:||||:    ||.|   ::.:|||
Mouse   317 KNSLRPRKMGELYLPKFSISTDYSLKNILPELGIKEIFSKQADLSGI----TGTKDLIVSQMVHK 377

  Fly   315 SFIEINERG----ASTGEASDHAESIQKKTRASTSFKVNRPFVFLI--RDKHTVYFRGRV 368
            :.:::.|.|    |:||.   :...:.::    ||...||.|:.:|  .|..|..|..::
Mouse   378 AVLDVAETGTEGVAATGV---NFRILSRR----TSLWFNRTFLMVISHTDVQTTLFIAKI 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Db	NP_001356884.1	SERPIN	22..368	CDD:238101	100/375 (27%)
Serpina3c	XP_011242304.1	serpinA3_A1AC	56..434	CDD:381019	102/385 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010