Protein Alignment Spn28Db and SERPINA12

DIOPT Version :9

• Sequence 1: NP_001356884.1
• Gene: Spn28Db / 326261
• FlyBaseID: FBgn0053121
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_001291390.1
• Gene: SERPINA12 / 145264
• HGNCID: 18359
• Length: 414
• Species: Homo sapiens
• Alignment Length: 393
• Identity: 93/393 - (23%)
• Similarity: 168/393 - (42%)
• Gaps: 86/393 - (21%)

  Fly    23 FKLNLLELVMDKAESNFIASPLCIEIGISMILMGAKGTTAEELRSVLDLPVDVTEMAKKYERIMS 87
            ||| |.:|.......|...|||.|....||:.:||:.:|.:|::...
Human    57 FKL-LKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGF------------------ 102

  Fly    88 NFQK------HNGLRFTNWLYVNETYEVRQDY-----NTLM-------KSTFMAEGKD------- 127
            ||:|      |.|..:    .::|..:..||.     |||.       :..|:.:.|:
Human   103 NFRKMPEKDLHEGFHY----IIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETI 163

  Fly   128 -------PLSQRKASNSISFSIHRKSHKGMRTISN-DHNLQINESAVLVNTVYYSGAWKTRFSKK 184
                   .::|::.::.||...|.|       |:| ..|:......:|.|.:::...||..|...
Human   164 LTNFQNLEMAQKQINDFISQKTHGK-------INNLIENIDPGTVMLLANYIFFRARWKHEFDPN 221

  Fly   185 DTKLKVFHGDHNKKVYVRMMSHVGRFRIA--DHSYGQIIEMPFDNSDLSMIIGLPLHNTYLSSIE 247
            .||.:.|..:.|..|.|.||...|.:::.  |.....|:|:|: ..:::.|..|| ....|..:|
Human   222 VTKEEDFFLEKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPY-QKNITAIFILP-DEGKLKHLE 284

  Fly   248 KILRT---------LSESLVENNVHVELPKFKIKYQTELVESLKKLGIHLIFSNTSDLSGLLTNG 303
            |.|:.         ||..:|:    |.:|:..:....:|.::|..:|:..||....||:.:..:
Human   285 KGLQVDTFSRWKTLLSRRVVD----VSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPH- 344

  Fly   304 TGAKINHVVHKSFIEINERGASTGEASDHAESIQKKTRASTSFKVNRPFVFLIRDKH--TVYFRG 366
            ...|:...|||:.::::||| :.|.|...|:::..:|  ....|:::|::.||..:.  :|.|.|
Human   345 RSLKVGEAVHKAELKMDERG-TEGAAGTGAQTLPMET--PLVVKIDKPYLLLIYSEKIPSVLFLG 406

  Fly   367 RVV 369
            ::|
Human   407 KIV 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Db	NP_001356884.1	SERPIN	22..368	CDD:238101	92/390 (24%)
SERPINA12	NP_001291390.1	serpinA12_vaspin	40..411	CDD:381026	93/393 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010