DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Db and Serpinc1

DIOPT Version :9

Sequence 1:	NP_001356884.1	Gene:	Spn28Db / 326261	FlyBaseID:	FBgn0053121	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_543120.1	Gene:	Serpinc1 / 11905	MGIID:	88095	Length:	465	Species:	Mus musculus

Alignment Length:	374	Identity:	95/374 - (25%)
Similarity:	180/374 - (48%)	Gaps:	31/374 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 KFKLNLLELVMDKA--ESNFIASPLCIEIGISMILMGAKGTTAEELRSVLDLPVDVTE------- 77
            :|..|..:.:.|..  ..|...|||.|....:|..:||...|.::|..|..... ::|
Mouse    90 RFATNFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLKQLMEVFKFDT-ISEKTSDQIH 153

  Fly    78 --MAKKYERIMSNFQKHNGLRFTNWLYVNETYEVRQDYNTLMKSTFMAEGKDPL----SQRKASN 136
              .||...|:.....|.:.|...|.|:.:::....:.|..:.:..:.|: ..||    :..::..
Mouse   154 FFFAKLNCRLYRKANKSSDLVSANRLFGDKSLTFNESYQDVSEVVYGAK-LQPLDFKENPEQSRV 217

  Fly   137 SISFSIHRKSHKGMRTISNDHNLQINESAVLVNTVYYSGAWKTRFSKKDTKLKVFHGDHNKKVYV 201
            :|:..:..|:...::.:.....:....:.|||||:|:.|.||::||.::|:.:.|:....:...|
Mouse   218 TINNWVANKTEGRIKDVIPQGAINELTALVLVNTIYFKGLWKSKFSPENTRKEPFYKVDGQSCPV 282

  Fly   202 RMMSHVGRF---RIADHSYGQIIEMPFDNSDLSMIIGLPLHNTYLSSIE-----KILRTLSESLV 258
            .||...|:|   |:|:.:  |::|:||...|::|::.||.....|:.:|     ::|:...:.|.
Mouse   283 PMMYQEGKFKYRRVAEGT--QVLELPFKGDDITMVLILPKPEKSLAKVEQELTPELLQEWLDELS 345

  Fly   259 ENNVHVELPKFKIKYQTELVESLKKLGIHLIFS-NTSDLSGLLTNG-TGAKINHVVHKSFIEINE 321
            |..:.|.:|:|:.:....|.|.|:.:|:..:|| ..|.|.|::..| ....::...||:|:|:||
Mouse   346 ETMLVVHMPRFRTEDGFSLKEQLQDMGLIDLFSPEKSQLPGIVAGGRDDLYVSDAFHKAFLEVNE 410

  Fly   322 RGASTGEASDHAESIQKKTRASTSFKVNRPFVFLIRD--KHTVYFRGRV 368
            .|:....::....:.:.......:||.||||:.|||:  .:|:.|.|||
Mouse   411 EGSEAAASTSVVITGRSLNPNRVTFKANRPFLVLIREVALNTIIFMGRV 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Db	NP_001356884.1	SERPIN	22..368	CDD:238101	93/372 (25%)
Serpinc1	NP_543120.1	serpinC1_AT3	71..464	CDD:381002	95/374 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.930