DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33116 and CHPT1

DIOPT Version :9

Sequence 1:	NP_788074.1	Gene:	CG33116 / 326259	FlyBaseID:	FBgn0053116	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_064629.2	Gene:	CHPT1 / 56994	HGNCID:	17852	Length:	406	Species:	Homo sapiens

Alignment Length:	432	Identity:	113/432 - (26%)
Similarity:	187/432 - (43%)	Gaps:	92/432 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LTQDQINGFDNYKYSAIDTS----PLSQYVMHPFWDWLVKFFPRWFAPNLMTFLGFLFSAM-NLV 73
            |:..|:...:.::|||...|    ||..|     |.||:::.|.|.|||.:|.||...:.: .||
Human    21 LSAAQLRRLEEHRYSAAGVSLLEPPLQLY-----WTWLLQWIPLWMAPNSITLLGLAVNVVTTLV 80

  Fly    74 LLSYYDWNFDASSGEEGTTPIPSWVWLCTAINIFLAYTLDGIDGKQARRIGLSGPLGELFDHGLD 138
            |:||.         ...|...|.|.:|..|:.:|:..:||.||||||||.....|||||||||.|
Human    81 LISYC---------PTATEEAPYWTYLLCALGLFIYQSLDAIDGKQARRTNSCSPLGELFDHGCD 136

  Fly   139 SYTAMLIPTCLYSIFGRSRVYSVRPMRMYYVCLTVYFNFFISHWEKYNTGIL------------Y 191
            |.:.:.:.... ||..|...|   |...::......|.|:.:||:.|.:|:|            .
Human   137 SLSTVFMAVGA-SIAARLGTY---PDWFFFCSFIGMFVFYCAHWQTYVSGMLRFGKVDVTEIQIA 197

  Fly   192 LPWGYDLSMWGSTAMYLVTWWMGFERWKFELPLGSYGTLPLGNVMEAVLHVSAMANLPLV----- 251
            |...:.||.:|...|           |.:.:|           ::|..|.:     ||::
Human   198 LVIVFVLSAFGGATM-----------WDYTIP-----------ILEIKLKI-----LPVLGFLGG 235

  Fly   252 IINVYNSYAH--------RTGRLLSFWEAVRPMWPFITYFVILLAWPY-VSPNDIMEKDPRAIFM 307
            :|...::|.|        :.|..::....:.| ...|...:||....| .|..|:.||.|....:
Human   236 VIFSCSNYFHVILHGGVGKNGSTIAGTSVLSP-GLHIGLIIILAIMIYKKSATDVFEKHPCLYIL 299

  Fly   308 LSGTIFSNVSCRLIVSQMSVTRCEAWHWQTPMFI---LSFLTSLWIPLL-ERPLLYLLLIVTTLS 368
            :.|.:|:.||.:|:|:.|  |:.|. :.|..:|:   |.||...:...: |..:|::.:::::..
Human   300 MFGCVFAKVSQKLVVAHM--TKSEL-YLQDTVFLGPGLLFLDQYFNNFIDEYVVLWMAMVISSFD 361

  Fly   369 HWQYGASVVNQMCEH-----FNRVCFTVHKRVPQEELPKKKT 405
            ...|.:::..|:..|     |...|   |:...|.::...|:
Human   362 MVIYFSALCLQISRHLHLNIFKTAC---HQAPEQVQVLSSKS 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33116	NP_788074.1	CDP-OH_P_transf	13..348	CDD:382018	103/367 (28%)
CHPT1	NP_064629.2	CDP-OH_P_transf	25..337	CDD:294308	100/360 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5050
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D847100at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820