DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33116 and CEPT1

DIOPT Version :9

Sequence 1:	NP_788074.1	Gene:	CG33116 / 326259	FlyBaseID:	FBgn0053116	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_001007795.1	Gene:	CEPT1 / 10390	HGNCID:	24289	Length:	416	Species:	Homo sapiens

Alignment Length:	397	Identity:	102/397 - (25%)
Similarity:	175/397 - (44%)	Gaps:	52/397 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LTQDQINGFDNYKYSAIDTSPLSQYVMHPFWDWLVKFFPRWFAPNLMTFLGFLFSAMNLVLLSYY 78
            |::.|:...:.::|.:...| |.:.:|..:|:|||:..|.|.||||:|.:|...:....:||.:|
Human    43 LSRHQLKRLEEHRYQSAGRS-LLEPLMQGYWEWLVRRVPSWIAPNLITIIGLSINICTTILLVFY 106

  Fly    79 DWNFDASSGEEGTTPIPSWVWLCTAINIFLAYTLDGIDGKQARRIGLSGPLGELFDHGLDSYTA- 142
                    ....|...|.|.::..|..:|:..:||.||||||||...|.|||||||||.||.:.
Human   107 --------CPTATEQAPLWAYIACACGLFIYQSLDAIDGKQARRTNSSSPLGELFDHGCDSLSTV 163

  Fly   143 -MLIPTCLYSIFGRSRVYSVRPMRMYYVCLTVYFNFFISHWEKYNTGILYLPWGYDLSMWGSTAM 206
             :::.||:....|      ..|..|::.|....|.|:.:||:.|.:|.|    .:.:.......:
Human   164 FVVLGTCIAVQLG------TNPDWMFFCCFAGTFMFYCAHWQTYVSGTL----RFGIIDVTEVQI 218

  Fly   207 YLVTWWMGFERWKFELPLGSYGTLPLGNVMEAVLHVS-----AMANLPLVIINVYNSY------- 259
            :::...:          |...|..|....|..||::.     |:..:...|.:..|.:
Human   219 FIIIMHL----------LAVIGGPPFWQSMIPVLNIQMKIFPALCTVAGTIFSCTNYFRVIFTGG 273

  Fly   260 AHRTGRLLSFWEAVRPMWPFITYFVILLAWPY-VSPNDIMEKDPRAIFMLSGTIFSNVSCRLIVS 323
            ..:.|..::....:.| :..|...:.|.|..| .|...:.||.|....:..|.:.:.::.:|:|:
Human   274 VGKNGSTIAGTSVLSP-FLHIGSVITLAAMIYKKSAVQLFEKHPCLYILTFGFVSAKITNKLVVA 337

  Fly   324 QMSVTRCEAWHWQTPMFI---LSFLTSLWIPLL-ERPLLYLLLIVTTLSHWQYGASVVNQMCEHF 384
            .|  |:.| .|.....||   |.||...:...: |..:|::.|:.:.....:|..||.||:..|.
Human   338 HM--TKSE-MHLHDTAFIGPALLFLDQYFNSFIDEYIVLWIALVFSFFDLIRYCVSVCNQIASHL 399

  Fly   385 NRVCFTV 391
            :...|.:
Human   400 HIHVFRI 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33116	NP_788074.1	CDP-OH_P_transf	13..348	CDD:382018	92/351 (26%)
CEPT1	NP_001007795.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
CEPT1	NP_001007795.1	CDP-OH_P_transf	43..407	CDD:412385	102/397 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5050
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D847100at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1820
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.850