back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment eIF4EHP and EIF4E3

DIOPT Version :9

Sequence 1:	NP_001163710.1	Gene:	eIF4EHP / 326255	FlyBaseID:	FBgn0053100	Length:	248	Species:	Drosophila melanogaster
Sequence 2:	NP_001128123.1	Gene:	EIF4E3 / 317649	HGNCID:	31837	Length:	224	Species:	Homo sapiens

Alignment Length:	200	Identity:	48/200 - (24%)
Similarity:	88/200 - (44%)	Gaps:	27/200 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 IDVDNLPPLEVGPGENRLQHTYCLWFSRKETQRAAADYSKSLHMVGRCASVQQWWSLYSHLIRPT 95
            :.:..|..|:..||...|..::..|..|......||:.:.:|..:....:||.:||:|:::...|
Human    32 LGLQQLSALQPEPGGVPLHSSWTFWLDRSLPGATAAECASNLKKIYTVQTVQIFWSVYNNIPPVT 96

  Fly    96 ALKPYRELLLFKQGIIPMWEDPANSKGGQWLIRLRKNKVDRAWENVCMAMLGEQF----LVGDEI 156
            :|.......|.:....|:||:.:|:|||.|.:::.|:.....|:.:.:|.:||||    ...||:
Human    97 SLPLRCSYHLMRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEV 161

  Fly   157 CGVVLQTKYPNPSIQVACSSRPIICIIYTRFVVQFGKCKIIIVTNNNKRNVYEFLTIIVIKI--- 218
            .||.:..:.....:||...:..::           |:..::       ..:||.|..|..|.
Human   162 IGVSVSVRDREDVVQVWNVNASLV-----------GEATVL-------EKIYELLPHITFKAVFY 208

  Fly   219 --HEE 221
              |||
Human   209 KPHEE 213

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.