Protein Alignment eIF4EHP and EIF4E1B

DIOPT Version :10

• Sequence 1: NP_001163710.1
• Gene: eIF4EHP / 326255
• FlyBaseID: FBgn0053100
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_001092878.1
• Gene: EIF4E1B / 253314
• HGNCID: 33179
• Length: 242
• Species: Homo sapiens
• Alignment Length: 140
• Identity: 50/140 - (35%)
• Similarity: 77/140 - (55%)
• Gaps: 8/140 - (5%)

  Fly    38 PLEVGPGENRLQHTYCLWFSRKETQRAAADYSKSLHMVGRCASVQQWWSLYSHLIRPTALKPYRE 102
            |:||....:.||:.:.|||.:.:..||..|   :||:|.:..:|:.:|:||||:...:.|....:
Human    54 PMEVKLELHPLQNRWALWFFKNDRSRAWQD---NLHLVTKVDTVEDFWALYSHIQLASKLSSGCD 115

  Fly   103 LLLFKQGIIPMWEDPANSKGGQWLIRLRKN----KVDRAWENVCMAMLGEQFLV-GDEICGVVLQ 162
            ..|||.||.|||||..|.:||:||:.|.|.    ::||.|....:.::||.|.. ..|:||.|:.
Human   116 YALFKDGIQPMWEDSRNKRGGRWLVSLAKQQRHIELDRLWLETLLCLIGESFEEHSREVCGAVVN 180

  Fly   163 TKYPNPSIQV 172
            .:.....|.|
Human   181 IRTKGDKIAV 190

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4EHP	NP_001163710.1	IF4E	48..>172	CDD:460281	46/128 (36%)
EIF4E1B	NP_001092878.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..42
		EIF4EBP1/2/3 binding. /evidence=ECO:0000250	62..65		0/2 (0%)
		IF4E	63..222	CDD:460281	47/131 (36%)
		EIF4EBP1/2/3 binding. /evidence=ECO:0000250	98..102		2/3 (67%)
		EIF4EBP1/2/3 binding. /evidence=ECO:0000250	157..164		0/6 (0%)