Protein Alignment eIF4EHP and EIF4E

DIOPT Version :10

• Sequence 1: NP_001163710.1
• Gene: eIF4EHP / 326255
• FlyBaseID: FBgn0053100
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_001124151.1
• Gene: EIF4E / 1977
• HGNCID: 3287
• Length: 248
• Species: Homo sapiens
• Alignment Length: 233
• Identity: 57/233 - (24%)
• Similarity: 105/233 - (45%)
• Gaps: 47/233 - (20%)

  Fly     6 VANKQYETKNWPDIVDSDDSDVDNQIDVDNLPPLEVGPGENRLQHTYCLWFSRKETQRAAADYSK 70
            :|..:.||...|:...:::...::..:|.| |...:   ::.||:.:.|||.:.:..:.   :..
Human     1 MATVEPETTPTPNPPTTEEEKTESNQEVAN-PEHYI---KHPLQNRWALWFFKNDKSKT---WQA 58

  Fly    71 SLHMVGRCASVQQWWSLYSHLIRPTALKPYRELLLFKQGIIPMWEDPANSKGGQWLIRL----RK 131
            :|.::.:..:|:.:|:||:|:...:.|.|..:..|||.||.|||||..|.:||:|||.|    |:
Human    59 NLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRR 123

  Fly   132 NKVDRAW-------------------------------ENVCMAMLGEQF-LVGDEICGVVLQTK 164
            :.:||.|                               |...:.::||.| ...|::||.|:..:
Human   124 SDLDRFWLETRWDLAMLPRLVSNFWPQVILPLQPPKVLELQLLCLIGESFDDYSDDVCGAVVNVR 188

  Fly   165 YPNPSIQV---ACSSRPIICIIYTRFVVQFG-KCKIII 198
            .....|.:   .|.:|..:..|...:..:.| ..||:|
Human   189 AKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVI 226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4EHP	NP_001163710.1	IF4E	48..>172	CDD:460281	43/159 (27%)
EIF4E	NP_001124151.1	IF4E	38..228	CDD:460281	50/192 (26%)