Protein Alignment eIF4EHP and Eif4e

DIOPT Version :10

• Sequence 1: NP_001163710.1
• Gene: eIF4EHP / 326255
• FlyBaseID: FBgn0053100
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_446426.1
• Gene: Eif4e / 117045
• RGDID: 69647
• Length: 217
• Species: Rattus norvegicus
• Alignment Length: 186
• Identity: 54/186 - (29%)
• Similarity: 91/186 - (48%)
• Gaps: 25/186 - (13%)

  Fly    35 NLPPLEVGPGENR-------------LQHTYCLWFSRKETQRAAADYSKSLHMVGRCASVQQWWS 86
            |.||.|....|:.             ||:.:.|||.:.:..:.   :..:|.::.:..:|:.:|:
  Rat    13 NPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKT---WQANLRLISKFDTVEDFWA 74

  Fly    87 LYSHLIRPTALKPYRELLLFKQGIIPMWEDPANSKGGQWLIRL----RKNKVDRAWENVCMAMLG 147
            ||:|:...:.|.|..:..|||.||.|||||..|.:||:|||.|    |::.:||.|....:.::|
  Rat    75 LYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIG 139

  Fly   148 EQF-LVGDEICGVVLQTKYPNPSIQV---ACSSRPIICIIYTRFVVQFG-KCKIII 198
            |.| ...|::||.|:..:.....|.:   .|.:|..:..|...:..:.| ..||:|
  Rat   140 ESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVI 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4EHP	NP_001163710.1	IF4E	48..>172	CDD:460281	42/128 (33%)
Eif4e	NP_446426.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27		5/13 (38%)
		EIF4EBP1/2/3 binding. /evidence=ECO:0000250|UniProtKB:P06730	37..40		0/2 (0%)
		IF4E	38..197	CDD:460281	49/161 (30%)
		EIF4EBP1/2/3 binding. /evidence=ECO:0000250|UniProtKB:P06730	73..77		2/3 (67%)
		EIF4EBP1/2/3 binding. /evidence=ECO:0000250|UniProtKB:P06730	132..139		0/6 (0%)