DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33096 and abhd12

DIOPT Version :9

Sequence 1:	NP_001356926.1	Gene:	CG33096 / 326251	FlyBaseID:	FBgn0053096	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_001070065.1	Gene:	abhd12 / 767657	ZFINID:	ZDB-GENE-060929-268	Length:	382	Species:	Danio rerio

Alignment Length:	286	Identity:	73/286 - (25%)
Similarity:	112/286 - (39%)	Gaps:	86/286 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 CPGPIAAKLAF-------------QPPEP------TYKLTPADDTNIRY----------NLQLFD 51
            ||. |.|||.|             :|.:.      .:.|.|.:..||..          ..|..|
Zfish    79 CPS-IQAKLVFLNFVRVPYFIDLKRPQDQGMNHTHNFYLQPEEGINIGVWHTVPAGMWREAQAKD 142

  Fly    52 RAEWQYSEREKSKVEAFFTRTSRGNLITCIYVRCSKNAKYTLLFSHGNAVDLG--QMSSFYLTLG 114
             |||                          |.:..:::...:|:.||||...|  .....|..|
Zfish   143 -AEW--------------------------YEKSFQSSHPVILYLHGNAGTRGGDHRVQLYKVL- 179

  Fly   115 SQINCNIFGYDYSGYGMSGGKPSEKNLYADIEAAWQAMRTRFNISPETIILYGQSIGTVPTVDLA 179
            |.:..::..:||.|:|.|.|.|||:.:.:|....:|.::.|  |.|:.:.::|.|:||....:|.
Zfish   180 SSLGYHVVTFDYRGWGDSEGSPSERGMTSDALFLYQWIKQR--IGPKPLYIWGHSLGTGVATNLV 242

  Fly   180 SR-----HEVGAVILHSPLMSGLR---------VVFRNTKR-TWFF-DA-------FPSIDKVAK 221
            .|     ....|:||.|| .:.:|         :|:|.... .||| ||       |.|.:.|..
Zfish   243 RRLCDRGTPPDALILESP-FTNIREEAKSHPFSMVYRYLPGFDWFFLDAISANDIRFASDENVNH 306

  Fly   222 VKAPVLVIHGTDDEVIDFSHGIGIYE 247
            :..|||::|..||.|:.|..|..:|:
Zfish   307 ISCPVLILHAEDDTVVPFQLGKKLYD 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33096	NP_001356926.1	FrsA	<92..280	CDD:223999	55/181 (30%)
abhd12	NP_001070065.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..45
abhd12	NP_001070065.1	Hydrolase_4	151..340	CDD:378820	55/186 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1073
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900