DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33096 and ABHD17C

DIOPT Version :9

Sequence 1:	NP_001356926.1	Gene:	CG33096 / 326251	FlyBaseID:	FBgn0053096	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_067037.1	Gene:	ABHD17C / 58489	HGNCID:	26925	Length:	329	Species:	Homo sapiens

Alignment Length:	316	Identity:	201/316 - (63%)
Similarity:	241/316 - (76%)	Gaps:	33/316 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 FSISELCCMFCCPPCPGPIAAKLAFQPPEPTYKL-------------TPADDTNI---------- 43
            ||:.|||.:|||||||..|||||||.||||||.:             .||..|..
Human    11 FSLGELCWLFCCPPCPSRIAAKLAFLPPEPTYTVLAPEQRGAGASAPAPAQATAAAAAAQPAPQQ 75

  Fly    44 ----------RYNLQLFDRAEWQYSEREKSKVEAFFTRTSRGNLITCIYVRCSKNAKYTLLFSHG 98
                      ..:|.|.:||:||||:||...||.||:||:|.|.:.|::|||:.:::||||||||
Human    76 PEEGAGAGPGACSLHLSERADWQYSQRELDAVEVFFSRTARDNRLGCMFVRCAPSSRYTLLFSHG 140

  Fly    99 NAVDLGQMSSFYLTLGSQINCNIFGYDYSGYGMSGGKPSEKNLYADIEAAWQAMRTRFNISPETI 163
            ||||||||.|||:.|||:||||||.|||||||:|.||||||||||||:|||||:|||:.:|||.|
Human   141 NAVDLGQMCSFYIGLGSRINCNIFSYDYSGYGVSSGKPSEKNLYADIDAAWQALRTRYGVSPENI 205

  Fly   164 ILYGQSIGTVPTVDLASRHEVGAVILHSPLMSGLRVVFRNTKRTWFFDAFPSIDKVAKVKAPVLV 228
            ||||||||||||||||||:|..||||||||||||||.|.:|::|:.|||||||||::||.:||||
Human   206 ILYGQSIGTVPTVDLASRYECAAVILHSPLMSGLRVAFPDTRKTYCFDAFPSIDKISKVTSPVLV 270

  Fly   229 IHGTDDEVIDFSHGIGIYERCPKTVEPFWVEGAGHNDVELHPHYYERLRKFLSVEL 284
            ||||:|||||||||:.:|||||:.|||.|||||||||:||:..|.|||::|:|.||
Human   271 IHGTEDEVIDFSHGLAMYERCPRAVEPLWVEGAGHNDIELYAQYLERLKQFISHEL 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33096	NP_001356926.1	FrsA	<92..280	CDD:223999	146/187 (78%)
ABHD17C	NP_067037.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	53..85		3/31 (10%)
ABHD17C	NP_067037.1	FrsA	<134..326	CDD:223999	148/191 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	189	1.000	Domainoid score	I3287
eggNOG	1	0.900	-	-		E1_COG1073
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H26429
Inparanoid	1	1.050	434	1.000	Inparanoid score	I1708
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45930
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000445
OrthoInspector	1	1.000	-	-		otm41667
orthoMCL	1	0.900	-	-		OOG6_100915
Panther	1	1.100	-	-	LDO	PTHR12277
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R134
SonicParanoid	1	1.000	-	-		X362
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.950