Protein Alignment P5CDh2 and ALDH1A2

DIOPT Version :9

• Sequence 1: NP_788705.1
• Gene: P5CDh2 / 32625
• FlyBaseID: FBgn0053092
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_003879.2
• Gene: ALDH1A2 / 8854
• HGNCID: 15472
• Length: 518
• Species: Homo sapiens
• Alignment Length: 516
• Identity: 130/516 - (25%)
• Similarity: 223/516 - (43%)
• Gaps: 96/516 - (18%)

  Fly    79 VEHVPIVINGQEFQAKEDFQQVLPYDIQQPIAHYGHAHRVL-IQMA----IDKSVEAQ------- 131
            :::..|.|| .|:|..|..:..       |:.:.....:|. :|.|    |||:|:|.
Human    35 IKYTKIFIN-NEWQNSESGRVF-------PVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLG 91

  Fly   132 VKWDKVRLSDRIDIWERAAMLIAGRYRYNIIAATM--LGQGKTLRQA-EMDV------------- 180
            ..|.::..|:|..:.::.|.|:.   |...:.|||  |..||...|| .:|:
Human    92 SVWRRMDASERGRLLDKLADLVE---RDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGW 153

  Fly   181 AELVDFMRINPV------FLRELANYEPIRDIQNNCRNSMRLRGLSGFVAAISPFNFTGIAANLA 239
            |:.:..|.| ||      |.|    :|||                 |....|.|:||..:.....
Human   154 ADKIHGMTI-PVDGDYFTFTR----HEPI-----------------GVCGQIIPWNFPLLMFAWK 196

  Fly   240 YTPAL-MGNSVIWKPSDSAILSNYFVFKALREAGVPDGVVNFVPAEETTFASVVTQHPKLAGINF 303
            ..||| .||:|:.||::...||..::...::|||.|.||:|.:|....|..:.:..|..:..|.|
Human   197 IAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAF 261

  Fly   304 TGTSTVLKVLWQLVAQNINFYQNYPRLVGEGGGKNFHFVHSSAEPETAVACTIRAAFEYAGQKCS 368
            ||::.|.|::.:...::     |..|:..|.|||:.:.:.:.|:.:.||....:..|...||.|:
Human   262 TGSTEVGKLIQEAAGRS-----NLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCT 321

  Fly   369 SCSMLYVPESLWQNHIREPLLEITASLVVRQ--DATYCDSFCSAVINRRAYDRIYMWLRYIDQ-- 429
            :.|.::|.||:::..:|.. :|.....||..  |.|   :.....|:::.|::|   |..|..
Human   322 AGSRIFVEESIYEEFVRRS-VERAKRRVVGSPFDPT---TEQGPQIDKKQYNKI---LELIQSGV 379

  Fly   430 SPSCQILVGGSCDKRRGYYVDPTVVLVKDLDNIICREELLAPILGVYVYPDHKLKETMEKVAQIN 494
            :...::..||....|:|::::|||......|..|.:||:..|:..:..:  ..:.|.:|:....:
Human   380 AEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRF--KTMDEVIERANNSD 442

  Fly   495 HGLTGSVFAQDQN---FIEEAYDAFRVNVGNLNVNDKSTGLMVGQQPFGAGHMTGTSDKLG 552
            .||..:||..|.|   .:..|..|..|.:...|.       :..|.|||...|:|...::|
Human   443 FGLVAAVFTNDINKALTVSSAMQAGTVWINCYNA-------LNAQSPFGGFKMSGNGREMG 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh2	NP_788705.1	ALDH-SF	50..570	CDD:299846	130/516 (25%)
ALDH1A2	NP_003879.2	ALDH_F1AB_F2_RALDH1	32..512	CDD:143459	130/516 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810