Protein Alignment P5CDh2 and ALD4

DIOPT Version :10

• Sequence 1: NP_788705.1
• Gene: P5CDh2 / 32625
• FlyBaseID: FBgn0053092
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_015019.1
• Gene: ALD4 / 854556
• SGDID: S000005901
• Length: 519
• Species: Saccharomyces cerevisiae
• Alignment Length: 501
• Identity: 121/501 - (24%)
• Similarity: 219/501 - (43%)
• Gaps: 57/501 - (11%)

  Fly    76 LNRVEHVPIVI-----NGQEFQ-------------AKED--FQQVLPYDIQQPIAHYGHAHRVLI 120
            |....|:|:.:     ||.|::             :|::  |:.:.| ..::.|.|........:
Yeast    21 LRYFSHLPMTVPIKLPNGLEYEQPTGLFINNKFVPSKQNKTFEVINP-STEEEICHIYEGREDDV 84

  Fly   121 QMAIDKSVEA--QVKWDKVRLSDRIDIWERAAMLIAGRYRYNIIAA-TMLGQGKTLRQAEMDVAE 182
            :.|:..:..|  ...|:.:...||.....|.|.||  ....::||: ..|..||.:..:..||..
Yeast    85 EEAVQAADRAFSNGSWNGIDPIDRGKALYRLAELI--EQDKDVIASIETLDNGKAISSSRGDVDL 147

  Fly   183 LVDFMRINPVFLRELANYEPIRDIQNNCRN-SMRLRGLSGFVAAISPFNFTGIAANLAYTPALM- 245
            ::::::.:..|..::..    |.|.....: |...|...|....|.|:||..:.......|||:
Yeast   148 VINYLKSSAGFADKIDG----RMIDTGRTHFSYTKRQPLGVCGQIIPWNFPLLMWAWKIAPALVT 208

  Fly   246 GNSVIWKPSDSAILSNYFVFKALREAGVPDGVVNFVPAEETTFASVVTQHPKLAGINFTGTSTVL 310
            ||:|:.|.::|..||..:|.|.:.:||:|.||:|.|..........:|.|||:..:.|||::...
Yeast   209 GNTVVLKTAESTPLSALYVSKYIPQAGIPPGVINIVSGFGKIVGEAITNHPKIKKVAFTGSTATG 273

  Fly   311 KVLWQLVAQNINFYQNYPRLVGEGGGKNFHFVHSSAEPETAVACTIRAAFEYAGQKCSSCSMLYV 375
            :.::|..|..:.      ::..|.|||:.:.|.:.||.:.||...|...:..:|:.|.:.|.:||
Yeast   274 RHIYQSAAAGLK------KVTLELGGKSPNIVFADAELKKAVQNIILGIYYNSGEVCCAGSRVYV 332

  Fly   376 PESLWQNHIREPLLEITASLVVRQDATYCDSFCSAVINRRAYDRIYMWLRYID--QSPSCQILVG 438
            .||::...|.|  .:..:..:...|.....:|..|..::...::|   |:|:|  ::....::.|
Yeast   333 EESIYDKFIEE--FKAASESIKVGDPFDESTFQGAQTSQMQLNKI---LKYVDIGKNEGATLITG 392

  Fly   439 GSCDKRRGYYVDPTVVLVKDLDNIICREELLAPILGVYVYPDHKLKETMEKVAQIN---HGLTGS 500
            |.....:||::.|||......|..|.:||:..|::.|     .|.|...|.:...|   :||...
Yeast   393 GERLGSKGYFIKPTVFGDVKEDMRIVKEEIFGPVVTV-----TKFKSADEVINMANDSEYGLAAG 452

  Fly   501 VFAQDQNFIEEAYDAFRVNVGNLNVNDKSTGLMVGQQPFGAGHMTG 546
            :...:.|...:..|  |||.|.:.:|..:.  .....|||..:.:|
Yeast   453 IHTSNINTALKVAD--RVNAGTVWINTYND--FHHAVPFGGFNASG 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh2	NP_788705.1	ALDH-SF	50..570	CDD:448367	121/501 (24%)
ALD4	NP_015019.1	ALDH_F1-2_Ald2-like	42..514	CDD:143410	115/480 (24%)