Protein Alignment P5CDh2 and aldh1a3

DIOPT Version :10

• Sequence 1: NP_788705.1
• Gene: P5CDh2 / 32625
• FlyBaseID: FBgn0053092
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_001038210.1
• Gene: aldh1a3 / 751785
• ZFINID: ZDB-GENE-061128-2
• Length: 513
• Species: Danio rerio
• Alignment Length: 534
• Identity: 131/534 - (24%)
• Similarity: 223/534 - (41%)
• Gaps: 99/534 - (18%)

  Fly    76 LNRVEHVPIVIN--------GQEFQAKEDFQQVLPYDIQQPIAHYGHAHRVLIQMAIDKSVEAQV 132
            :..::|..|.||        |::|........|...||::       |.:..:..|:..:..|..
Zfish    26 ITEIKHTKIFINNEWHTSSKGKQFPTINPATGVKICDIEE-------ADKADVDEAVKAAKAAGQ 83

  Fly   133 K---WDKV------RLSDRI-DIWERAAMLIA-------GRYRYNIIAATMLGQGKTLRQ----- 175
            :   |.::      ||.:|: |:.||...::|       |:...:.....:.|..||||.
Zfish    84 RGSVWRRMDASSRGRLLNRLADLLERERAVLATLESKDTGKPFLHAFFVDLDGSIKTLRYYAGWT 148

  Fly   176 -----AEMDVAE-LVDFMRINPVFLRELANYEPIRDIQNNCRNSMRLRGLSGFVAAISPFNFTGI 234
                 ..|.|.| .|.|.:           :|||                 |...||.|:||..:
Zfish   149 DKIHGKTMPVDENFVCFTK-----------HEPI-----------------GVCGAIIPWNFPLL 185

  Fly   235 AANLAYTPAL-MGNSVIWKPSDSAILSNYFVFKALREAGVPDGVVNFVPAEETTFASVVTQHPKL 298
            .......||| .||:|:.||::...|:...|...::|||.|.||||.||....|..:.:..|..:
Zfish   186 MLMWKIAPALACGNTVVLKPAEQTPLTALHVAALIKEAGFPPGVVNVVPGFGPTAGAAIAGHMNI 250

  Fly   299 AGINFTGTSTVLKVLWQLVAQNINFYQNYPRLVGEGGGKNFHFVHSSAEPETAVACTIRAAFEYA 363
            ..:.|||::.|.:::....|.:     |..|:..|.||||...|.:.::.:.||..|.:.||...
Zfish   251 DKLAFTGSTEVGQLVKAAAASS-----NLKRVTLELGGKNPCIVFADSDLQLAVEETQKGAFFNQ 310

  Fly   364 GQKCSSCSMLYVPESLWQNHIREPLLEITASLVVRQDATYCDSFCSAVINRRAYDRIYMWLRYID 428
            ||.|::.|.:||.|.:::..:|  |....|..:|..|.....:.....|::..:::|   |..:|
Zfish   311 GQACTAASRVYVQEPVYEEFVR--LSVERAKNIVIGDPMEPRTSHGPQIDQHQFEKI---LALVD 370

  Fly   429 --QSPSCQILVGGSCDKRRGYYVDPTVVL-VKDLDNIICREELLAPILGVYVYPDHKLKETMEKV 490
              :....::..||...:.||.::.||:.. ||| ...|.:||:..|:..:..:...  ::.:::.
Zfish   371 SGKKEGAKLEFGGCAVEDRGLFIHPTIFSDVKD-HMRIAKEEIFGPVQCIMKFECQ--QDVIDRA 432

  Fly   491 AQINHGLTGSVFAQDQN---FIEEAYDAFRVNVGNLNVNDKSTGLMVGQQPFGAGHMTGTSDKLG 552
            .....|||.:||.:|..   .:..|.:|..|.|...|.       :..|.|||...|:|...:||
Zfish   433 NSSQFGLTAAVFTRDVQRAMSVSAALEAGTVWVNCYNA-------LHAQTPFGGYKMSGNGRELG 490

  Fly   553 TPHSLLRWTSPQVI 566
             .::|..:|..:.|
Zfish   491 -EYALAEYTEVKAI 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh2	NP_788705.1	ALDH-SF	50..570	CDD:448367	131/534 (25%)
aldh1a3	NP_001038210.1	ALDH_F1AB_F2_RALDH1	28..506	CDD:143459	131/532 (25%)