Protein Alignment P5CDh2 and ALDH8A1

DIOPT Version :9

• Sequence 1: NP_788705.1
• Gene: P5CDh2 / 32625
• FlyBaseID: FBgn0053092
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_072090.1
• Gene: ALDH8A1 / 64577
• HGNCID: 15471
• Length: 487
• Species: Homo sapiens
• Alignment Length: 476
• Identity: 110/476 - (23%)
• Similarity: 189/476 - (39%)
• Gaps: 97/476 - (20%)

  Fly   120 IQMAIDKSVEAQVKWDKVRLSDRIDIWERAAMLIAGRYRYNIIAATMLGQGKTLRQAE-MDVAEL 183
            |:.|:..:.||...|......:|..:..:.|.|:..... ....|....|||||..|. ||:...
Human    47 IEAAVKAAREAFPSWSSRSPQERSRVLNQVADLLEQSLE-EFAQAESKDQGKTLALARTMDIPRS 110

  Fly   184 VDFMRINPVFLRELANYEPIRDIQNNCRNSMR--LRGLSGFVAAISPFNFTGIAANLAYTPAL-M 245
            |...|    |....:.:......|.:....|.  :|...|....|||:|...........||: .
Human   111 VQNFR----FFASSSLHHTSECTQMDHLGCMHYTVRAPVGVAGLISPWNLPLYLLTWKIAPAMAA 171

  Fly   246 GNSVIWKPSDSAILSNYFVFKALREAGVPDGVVNFVPAEETTFASVVTQHPKLAGINFTGTSTVL 310
            ||:||.|||:...::.:.:.|.|.:||||.||||.|..........:..||::..|:|||:....
Human   172 GNTVIAKPSELTSVTAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTA 236

  Fly   311 KVLWQLVAQNINFYQNYPRLVGEGGGKNFHFVHSSAEPETAVACTIRAAFEYAGQKCSSCSMLYV 375
            :.:.||.|.:..      :|..|.||||...:...|..:..:..|:|::|...|:.|...|.::|
Human   237 ERITQLSAPHCK------KLSLELGGKNPAIIFEDANLDECIPATVRSSFANQGEICLCTSRIFV 295

  Fly   376 PESLWQNHIR---------------EPLLEITASLVVRQDATYCDSFCSAVINRRAYDRIYMWLR 425
            .:|::...::               :||:.|                 .|:|::...:::..:::
Human   296 QKSIYSEFLKRFVEATRKWKVGIPSDPLVSI-----------------GALISKAHLEKVRSYVK 343

  Fly   426 YIDQSPSCQILVGGSCDK-------RRGYYVDPTVVL-VKDLDNIICREELLAPILGVYVYPDHK 482
            .. .:...||..|...||       :.||::.|||:. :|| ::....||:..|:  ..|.|...
Human   344 RA-LAEGAQIWCGEGVDKLSLPARNQAGYFMLPTVITDIKD-ESCCMTEEIFGPV--TCVVPFDS 404

  Fly   483 LKETMEKVAQINHGLTGSVFAQDQNFIEEAYDAFRVNVGNLNVNDKSTGLMVGQQPFGAGHMTGT 547
            .:|.:|:...:.:||..:|::.              |||.::                     ..
Human   405 EEEVIERANNVKYGLAATVWSS--------------NVGRVH---------------------RV 434

  Fly   548 SDKLGTPHSLLRWTSPQVIKE 568
            :.||   .|.|.||:..:|:|
Human   435 AKKL---QSGLVWTNCWLIRE 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh2	NP_788705.1	ALDH-SF	50..570	CDD:299846	110/476 (23%)
ALDH8A1	NP_072090.1	ALDH_F8_HMSADH	27..485	CDD:143412	110/476 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810