Protein Alignment P5CDh2 and Aldh1l1

DIOPT Version :9

• Sequence 1: NP_788705.1
• Gene: P5CDh2 / 32625
• FlyBaseID: FBgn0053092
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_071992.2
• Gene: Aldh1l1 / 64392
• RGDID: 621294
• Length: 902
• Species: Rattus norvegicus
• Alignment Length: 628
• Identity: 133/628 - (21%)
• Similarity: 235/628 - (37%)
• Gaps: 147/628 - (23%)

  Fly     6 AHGIVSNMRSIL---PRLEASV---KGGLVS---VRSTSKRPELSEHFTL---DEMVAN------ 52
            |..:.|:...||   |.:|.|.   |.|..|   ||...:..||.:...|   |..:|.
  Rat   324 AEAVRSSWMRILPNVPEVEDSTDFFKSGAASVDVVRLVEEVKELCDGLELENEDVYMATTFRGFI 388

  Fly    53 EKLLQYDEGSKERTELETALLGVLNRVE--------HVP--IVINGQ--EFQAKEDFQQVLPYDI 105
            :.|::...|..:.:|.      |:|.||        .:|  :.|.|:  :.:..:.:..:.|.|
  Rat   389 QLLVRKLRGEDDESEC------VINYVEKAVNKLTLQMPYQLFIGGEFVDAEGSKTYNTINPTD- 446

  Fly   106 QQPIAHYGHAHRVLIQMA------IDKSVEAQVK------WDKVRLSDRIDIWERAAMLIAGRYR 158
                      ..|:.|::      :||:|.|..:      |.|:...||            ||..
  Rat   447 ----------GSVICQVSLAQVSDVDKAVAAAKEAFENGLWGKINARDR------------GRLL 489

  Fly   159 YNIIAATMLGQGKTLRQAEMDVAELVDFMRINPVFLRELANYE-------------------PIR 204
            |.:  |.::.|    .|.|:...|.:|...:..:.|:......                   ||.
  Rat   490 YRL--ADVMEQ----HQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGATIPIN 548

  Fly   205 DIQNNCRNSMRLRGLSGFVAAISPFNFT------GIAANLAYTPALMGNSVIWKPSDSAILSNYF 263
            ..:.|...::..:...|....:.|:|:.      ..||.||     .||:|:.||:....|:...
  Rat   549 QARPNRNLTLTKKEPVGVCGIVIPWNYPLMMLSWKTAACLA-----AGNTVVIKPAQVTPLTALK 608

  Fly   264 VFKALREAGVPDGVVNFVPAEETTFASVVTQHPKLAGINFTGTSTVLKVLWQLVAQNINFYQNYP 328
            ..:...:||:|.||||.:|...:.....::.||.:..|.|||::.|.|.:.:..|     ..|..
  Rat   609 FAELTLKAGIPKGVVNILPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCA-----LSNVK 668

  Fly   329 RLVGEGGGKNFHFVHSSAEPETAVACTIRAAFEYAGQKCSSCSMLYVPESLWQNHIREPLLEITA 393
            ::..|.|||:...:.:..:...||...:.:.|...|:.|.:...|:|.||:....:::.:.|:..
  Rat   669 KVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEESIHNQFVQKVVEEVEK 733

  Fly   394 SLV---VRQDATYCDSFCSAVINRRAYDRIYMWLRYIDQSPSCQ--------ILVGGSCDKRRGY 447
            ..:   :.:|..:...      |..|:      ||.:.:  .||        ::.||:...|.|:
  Rat   734 MKIGNPLERDTNHGPQ------NHEAH------LRKLVE--YCQRGVKEGATLVCGGNQVPRPGF 784

  Fly   448 YVDPTVVLVKDLDNIICREELLAPILGVYVYPDHKLKETMEKVAQINHGLTGSVFAQDQN---FI 509
            :..|||....:....|.:||...||:.:..:.|..:...:.:......||...||.:|.|   ::
  Rat   785 FFQPTVFTDVEDHMYIAKEESFGPIMIISRFADGDVDAVLSRANATEFGLASGVFTRDINKALYV 849

  Fly   510 EEAYDAFRVNVGNLNVNDKSTGLMVGQQPFGAGHMTGTSDKLG 552
            .:...|..|.:...|..|.:.       |||....:|....||
  Rat   850 SDKLQAGTVFINTYNKTDVAA-------PFGGFKQSGFGKDLG 885

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh2	NP_788705.1	ALDH-SF	50..570	CDD:299846	117/572 (20%)
Aldh1l1	NP_071992.2	GART	1..203
		Substrate binding. /evidence=ECO:0000250	88..90
		Aldehyde dehydrogenase	417..902		109/529 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900