Protein Alignment P5CDh2 and Aldh1a3

DIOPT Version :9

• Sequence 1: NP_788705.1
• Gene: P5CDh2 / 32625
• FlyBaseID: FBgn0053092
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_444310.3
• Gene: Aldh1a3 / 56847
• MGIID: 1861722
• Length: 512
• Species: Mus musculus
• Alignment Length: 479
• Identity: 121/479 - (25%)
• Similarity: 216/479 - (45%)
• Gaps: 82/479 - (17%)

  Fly   124 IDKSVE-AQVKWDKVRLSDRIDIWERAAML-----IAGRYRYNIIAATMLGQGKTLRQA-EMDVA 181
            :||:|| ||..:.:.....|:|...|..:|     :..|.|..:.....:..||....| .:|:.
Mouse    71 VDKAVEAAQAAFQRGSPWRRLDALSRGQLLHQLADLVERDRAILATLETMDTGKPFLHAFFVDLE 135

  Fly   182 ELVDFMRI-----------------NPV-FLRELANYEPIRDIQNNCRNSMRLRGLSGFVAAISP 228
            ..:...|.                 |.| |.|    :|||                 |...||:|
Mouse   136 GCIKTFRYFAGWADKIQGRTIPTDDNVVCFTR----HEPI-----------------GVCGAITP 179

  Fly   229 FNFTGIAANLAYTPAL-MGNSVIWKPSDSAILSNYFVFKALREAGVPDGVVNFVPAEETTFASVV 292
            :||..:.......||| .||:|:.||::...|:..::...::|.|.|.||||.||....|..:.:
Mouse   180 WNFPLLMLAWKLAPALCCGNTVVLKPAEQTPLTALYLASLIKEVGFPPGVVNIVPGFGPTVGAAI 244

  Fly   293 TQHPKLAGINFTGTSTVLKVLWQLVAQNINFYQNYPRLVGEGGGKNFHFVHSSAEPETAVACTIR 357
            :.||::..|.|||::.|.|::.:..:::     |..|:..|.||||...|.:.|:.:.||.|..:
Mouse   245 SSHPQINKIAFTGSTEVGKLVREAASRS-----NLKRVTLELGGKNPCIVCADADLDLAVECAHQ 304

  Fly   358 AAFEYAGQKCSSCSMLYVPESLWQNHIREPLLEITASLVVRQDATYCDSFCSAV-----INRRAY 417
            ..|...||.|::.|.::|.|.::...:|.       |:...:.....|.|.:..     |:::.:
Mouse   305 GVFFNQGQCCTAASRVFVEEQVYGEFVRR-------SVEFAKKRPVGDPFDAKTEQGPQIDQKQF 362

  Fly   418 DRIYMWLRYID--QSPSCQILVGGSCDKRRGYYVDPTVVLVKDL-DNI-ICREELLAPILGVYVY 478
            |:|   |..|:  :....::..|||..:.||.::.|||  ..|: ||: |.:||:..|:..:..:
Mouse   363 DKI---LELIESGKKEGAKLECGGSAMEDRGLFIKPTV--FSDVTDNMRIAKEEIFGPVQPILKF 422

  Fly   479 PDHKLKETMEKVAQINHGLTGSVFAQDQNFIEEAYD-AFRVNVGNLNVNDKSTGLMVGQQPFGAG 542
            .:  |:|.:::....::|||.:||.::   :::|.. |..:..|.:.:|  .......|.|||..
Mouse   423 KN--LEEVIKRANSTDYGLTAAVFTKN---LDKALKLAAALESGTVWIN--CYNAFYAQAPFGGF 480

  Fly   543 HMTGTSDKLGTPHSLLRWTSPQVI 566
            .|:|...:|| .::|..:|..:.:
Mouse   481 KMSGNGRELG-EYALAEYTEVKTV 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh2	NP_788705.1	ALDH-SF	50..570	CDD:299846	121/479 (25%)
Aldh1a3	NP_444310.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22
		ALDH_F1AB_F2_RALDH1	26..506	CDD:143459	121/479 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810