Protein Alignment P5CDh2 and aldh8a1

DIOPT Version :10

• Sequence 1: NP_788705.1
• Gene: P5CDh2 / 32625
• FlyBaseID: FBgn0053092
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_001004540.1
• Gene: aldh8a1 / 447801
• ZFINID: ZDB-GENE-040912-3
• Length: 487
• Species: Danio rerio
• Alignment Length: 484
• Identity: 111/484 - (22%)
• Similarity: 200/484 - (41%)
• Gaps: 89/484 - (18%)

  Fly   120 IQMAIDKSVEAQVKWDKVRLSDRIDIWERAAMLIAGRYRYNIIAATMLGQGKTLRQA-EMDVAEL 183
            :..|:..:.||...|.....:||..:..:.|.||..|.. ..:.|....||||:..| .:|:...
Zfish    47 VNAAVRAAKEAFPDWSAKSPADRSKVLNKLADLIEARLE-EFVQAESKDQGKTITFARNVDIPRS 110

  Fly   184 VDFMRINPVFLRELANYEPIRDIQNNCRN-------SMRLRGLSGFVAAISPFNFTGIAANLAYT 241
            ....|.   |...:.::      .|:|..       :..:|...|....|||:|...........
Zfish   111 AYNFRF---FASSVLHH------TNDCSQMDHMGCLNYTIRCPVGVAGLISPWNLPLYLLTWKIA 166

  Fly   242 PAL-MGNSVIWKPSDSAILSNYFVFKALREAGVPDGVVNFVPAEETTFASVVTQHPKLAGINFTG 305
            ||: .||:|:.|||:...::.:.:.:.|.|||.|.||||.|..........:..||.:..|:|||
Zfish   167 PAVATGNTVVAKPSEMTSVTAWMMCQLLEEAGFPPGVVNIVFGTGPRAGDALVSHPDVPLISFTG 231

  Fly   306 TSTVLKVLWQLVAQNINFYQNYPRLVGEGGGKNFHFVHSSAEPETAVACTIRAAFEYAGQKCSSC 370
            ::...:::.:..|.:..      :|..|.||||...:.:.|:.|..::.|:|::|...|:.|...
Zfish   232 STATARLITERSAPHCK------KLSLELGGKNPAIIFADADMEQCISTTVRSSFSNQGEICLCT 290

  Fly   371 SMLYVPESLWQNHIREPLLEITASLVVRQDATYCDSFCS----AVINRRAYDRI--YMWLRYIDQ 429
            |.::|..|::...:.. .:|.|     |:..|...|..|    |:|::....::  |:.|...:
Zfish   291 SRIFVERSVYPEFLTR-FVEAT-----RRWKTGVPSDPSNDNGALISKEHLQKVKGYITLALAE- 348

  Fly   430 SPSCQILVGGSCDKRR-------GYYVDPTVVL-VKDLDNIICREELLAPILGVYVYPDHKLKET 486
              ..|:..|...||..       ||::.||::. ||| .:.:.:||:..|:  ..|.|..:.:|.
Zfish   349 --GAQVHCGEGVDKLALPQQNIGGYFMLPTIISGVKD-SSALMQEEIFGPV--TCVTPFDEEEEV 408

  Fly   487 MEKVAQINHGLTGSVFAQDQNFIEEAYDAFRVNVG----------NLNVNDKSTGLMVGQQPFGA 541
            :.:...:.:||:.:|:::|...:...  |.::..|          :||:            |||.
Zfish   409 ISRANNVRYGLSATVWSRDVGRVHRV--ARKLQAGLVWTNCWLVRDLNL------------PFGG 459

  Fly   542 GHMTGTSDKLGTPHSLLRWTSPQVIKESY 570
            ...:|...:.|              |:||
Zfish   460 MKHSGIGREGG--------------KDSY 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh2	NP_788705.1	ALDH-SF	50..570	CDD:448367	109/482 (23%)
aldh8a1	NP_001004540.1	ALDH_F8_HMSADH	27..485	CDD:143412	111/484 (23%)