DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment P5CDh2 and Aldh16a1

DIOPT Version :9

Sequence 1:	NP_788705.1	Gene:	P5CDh2 / 32625	FlyBaseID:	FBgn0053092	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_001028878.1	Gene:	Aldh16a1 / 361571	RGDID:	1566295	Length:	802	Species:	Rattus norvegicus

Alignment Length:	234	Identity:	50/234 - (21%)
Similarity:	94/234 - (40%)	Gaps:	50/234 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 IQMAIDKSVEAQVKWDKVRLSDRID-IWERAAMLIAGRYRYNIIAATM--LGQGKTLRQAEMDVA 181
            |:.|::.:.:|...|.......|.. :|..||.|   ..|..::||.:  .|...|:.:.|::::
  Rat   566 IRGAVEAAHQAAPGWGAQSPRARASLLWALAAAL---ERRKQVLAAQLERHGAAPTVAETEVELS 627

  Fly   182 ELVDFMRINPVFLRELANYEP-IRDIQNNCRNS------MRLRGLSGFVAAISPFNFTGIAANLA 239
                        :|.|..:.. ::|.....:.:      :|||...|.:|.:.|..:..:|....
  Rat   628 ------------VRRLQTWATRVQDQGQTLQVTGLRGPVLRLREPLGVLAVVCPDEWPMLAFVSL 680

  Fly   240 YTPALM-GNSVIWKPSDSAILSNYFVFKALRE--AGVPDGVVNFVPAEETTFASVVTQHPKLAGI 301
            ..|||. ||:|:..||.|..|   ...:|.::  |..|.|:||.|..:.......:..|..:..:
  Rat   681 LAPALAHGNAVVLVPSGSCPL---LALEACQDIAALFPAGLVNVVTGDRDHLTRCLALHQDVQAM 742

  Fly   302 NFTGTST-----------VLKVLWQLVAQNINFYQNYPR 329
            .:.|::.           .||.:|      :|  :::||
  Rat   743 WYFGSAQGSQFVEWASAGNLKPVW------VN--RDFPR 773

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh2	NP_788705.1	ALDH-SF	50..570	CDD:299846	50/234 (21%)
Aldh16a1	NP_001028878.1	ALDH-SF	19..491	CDD:416387
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	513..554
		ALDH-SF	550..>765	CDD:416387	46/216 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900