Protein Alignment P5CDh2 and Aldh2

DIOPT Version :9

• Sequence 1: NP_788705.1
• Gene: P5CDh2 / 32625
• FlyBaseID: FBgn0053092
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_115792.2
• Gene: Aldh2 / 29539
• RGDID: 69219
• Length: 519
• Species: Rattus norvegicus
• Alignment Length: 534
• Identity: 137/534 - (25%)
• Similarity: 214/534 - (40%)
• Gaps: 115/534 - (21%)

  Fly    84 IVINGQEFQA--KEDFQQVLPYDIQQPIAHYGHAHRVLIQMA------IDKSVEAQ-------VK 133
            |.||.:...|  |:.|..|.|           ....|:.|:|      :||:|:|.       ..
  Rat    41 IFINNEWHDAVSKKTFPTVNP-----------STGEVICQVAEGNKEDVDKAVKAARAAFQLGSP 94

  Fly   134 WDKVRLSDRIDIWERAAMLIAGRYRYNIIAATMLGQGKTLRQAEMDVAELVDF------------ 186
            |.::..|||..:..|.|.||. |.|..:.|...|..||     ...::.|||.
  Rat    95 WRRMDASDRGRLLYRLADLIE-RDRTYLAALETLDNGK-----PYVISYLVDLDMVLKCLRYYAG 153

  Fly   187 ---------MRINPVFLRELANYEPIRDIQNNCRNSMRLRGLSGFVAAISPFNFTGIAANLAYTP 242
                     :.|:..|. ....:||:                 |....|.|:||..:.......|
  Rat   154 WADKYHGKTIPIDGDFF-SYTRHEPV-----------------GVCGQIIPWNFPLLMQAWKLGP 200

  Fly   243 AL-MGNSVIWKPSDSAILSNYFVFKALREAGVPDGVVNFVPAEETTFASVVTQHPKLAGINFTGT 306
            || .||.|:.|.::...|:..:|...::|||.|.||||.||....|..:.:..|..:..:.|||
  Rat   201 ALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTG- 264

  Fly   307 STVLKVLWQLVAQNINFYQNYPRLVGEGGGKNFHFVHSSAEPETAVACTIRAAFEYAGQKCSSCS 371
            ||.:..|.|:.|.:    .|..|:..|.|||:.:.:.|.|:.:.||.....|.|...||.|.:.|
  Rat   265 STEVGHLIQVAAGS----SNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGS 325

  Fly   372 MLYVPESLWQNHIREPLLEITASLVVRQDATYCDSFCSAV-----INRRAYDRIYMWLRYI--DQ 429
            ..:|.|.::...:...:....:.:|       .:.|.|..     ::...:.:|   |.||  .|
  Rat   326 RTFVQEDVYDEFVERSVARAKSRVV-------GNPFDSRTEQGPQVDETQFKKI---LGYIKSGQ 380

  Fly   430 SPSCQILVGGSCDKRRGYYVDPTVV-LVKDLDNIICREELLAPILGVYVYPDHKLKETMEKVAQI 493
            ....::|.||.....|||::.|||. .||| ...|.:||:..|::.:.     |.|...|.|.:.
  Rat   381 QEGAKLLCGGGAAADRGYFIQPTVFGDVKD-GMTIAKEEIFGPVMQIL-----KFKTIEEVVGRA 439

  Fly   494 N---HGLTGSVFAQD---QNFIEEAYDAFRVNVGNLNVNDKSTGLMVGQQPFGAGHMTGTSDKLG 552
            |   :||..:||.:|   .|::.:|..|..|.:...:|       ...|.|||...|:|:..:||
  Rat   440 NNSKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDV-------FGAQSPFGGYKMSGSGRELG 497

  Fly   553 TPHSLLRWTSPQVI 566
             .:.|..:|..:.:
  Rat   498 -EYGLQAYTEVKTV 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh2	NP_788705.1	ALDH-SF	50..570	CDD:299846	137/534 (26%)
Aldh2	NP_115792.2	ALDH_F1AB_F2_RALDH1	33..513	CDD:143459	137/534 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810