Protein Alignment P5CDh2 and Aldh5a1

DIOPT Version :10

• Sequence 1: NP_788705.1
• Gene: P5CDh2 / 32625
• FlyBaseID: FBgn0053092
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_074042.1
• Gene: Aldh5a1 / 291133
• RGDID: 621422
• Length: 523
• Species: Rattus norvegicus
• Alignment Length: 461
• Identity: 107/461 - (23%)
• Similarity: 189/461 - (40%)
• Gaps: 87/461 - (18%)

  Fly   123 AIDKSVEAQVKWDKVRLSDRIDIWERAAMLIAGRYRYN-----------IIAATMLGQGKTLRQA 176
            |:..:.:|...|.:      |.:.||:::|   |..|:           ||.|.   .||.|::|
  Rat    89 AVRAAYDAFSSWKE------ISVKERSSLL---RKWYDLMIQNKDELAKIITAE---SGKPLKEA 141

  Fly   177 EMDVAELVDFMRINPVFLRELAN-------YEPIRDIQNNCRNSMRLRGLSGFVAAISPFNFTG- 233
            :.::.....|:.    :..|.|.       |...:|     :..:.|:...|..:.|:|:||..
  Rat   142 QGEILYSAFFLE----WFSEEARRVYGDIIYTSAKD-----KRGLVLKQPVGVASIITPWNFPSA 197

  Fly   234 -----IAANLAYTPALMGNSVIWKPSDSAILSNYFVFKALREAGVPDGVVNFVPAEET---TFAS 290
                 :.|.||     .|.:|:.||::....|...:.:...:||:|.||.|.:|...|   ....
  Rat   198 MITRKVGAALA-----AGCTVVVKPAEDTPYSALALAQLANQAGIPPGVYNVIPCSRTKAKEVGE 257

  Fly   291 VVTQHPKLAGINFTGTSTVLKVLWQLVAQNINFYQNYPRLVGEGGGKNFHFVHSSAEPETAVACT 355
            |:...|.::.|:|||::...|:|....|.::.      |:..|.||.....|..||..:.|||..
  Rat   258 VLCTDPLVSKISFTGSTATGKILLHHAANSVK------RVSMELGGLAPFIVFDSANVDQAVAGA 316

  Fly   356 IRAAFEYAGQKCSSCSMLYVPESLWQNHIREPLLEITASLVV----RQDATYCDSFCSAVINRRA 416
            :.:.|..|||.|...:...|...:..:.:.:....:..||.|    .:..|.     ..:||.:|
  Rat   317 MASKFRNAGQTCVCSNRFLVQRGIHDSFVTKFAEAMKKSLRVGNGFEEGTTQ-----GPLINEKA 376

  Fly   417 YDRIYMWLRYIDQ--SPSCQILVGGSCDKRRGYYVDPTVVLVKDLDNIICREELLAPILGVYVYP 479
            .:::.   ::::.  :....::.||...:..|.:.:||::.....|.:...||...|:.     |
  Rat   377 VEKVE---KHVNDAVAKGATVVTGGKRHQSGGNFFEPTLLSNVTRDMLCITEETFGPLA-----P 433

  Fly   480 DHKLKETMEKVAQINH---GLTGSVFAQDQNFIEEAYDAFRVNVGNLNVNDKSTGLMVGQQ-PFG 540
            ..|..:..|.||..|.   ||.|..::||...|...  |.::.||.:.||:   ||:...: |||
  Rat   434 VIKFDKEEEAVAIANAADVGLAGYFYSQDPAQIWRV--AEQLEVGMVGVNE---GLISSVECPFG 493

  Fly   541 AGHMTG 546
            ....:|
  Rat   494 GVKQSG 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh2	NP_788705.1	ALDH-SF	50..570	CDD:448367	107/461 (23%)
Aldh5a1	NP_074042.1	SSADH	66..516	CDD:188167	107/461 (23%)