Protein Alignment P5CDh2 and ALDH3A2

DIOPT Version :10

• Sequence 1: NP_788705.1
• Gene: P5CDh2 / 32625
• FlyBaseID: FBgn0053092
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_001026976.1
• Gene: ALDH3A2 / 224
• HGNCID: 403
• Length: 508
• Species: Homo sapiens
• Alignment Length: 437
• Identity: 94/437 - (21%)
• Similarity: 163/437 - (37%)
• Gaps: 96/437 - (21%)

  Fly   157 YRYNIIAATMLGQGKTLRQAEMDVAELVDFMRINPVFLRELANYEPIRDIQNNCRNSMRLRGLS- 220
            |...:|  |:||:              :|||..|   |.|....:|::      :|.:.:...:
Human    57 YSQEVI--TVLGE--------------IDFMLEN---LPEWVTAKPVK------KNVLTMLDEAY 96

  Fly   221 ------GFVAAISPFNFTGIAANLAYTPAL----MGNSVIWKPSDSAILSNYFVFKALRE----- 270
                  |.|..|..:|:..:   |...|.:    .||:||.|||:.:..:...:.|.|.:
Human    97 IQPQPLGVVLIIGAWNYPFV---LTIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQD 158

  Fly   271 --AGVPDGVVNFVPAEETTFASVVTQHPKLAGINFTGTSTVLKVLWQLVAQNINFYQNYPRLVGE 333
              ..:..||      ||||  .::.|  :...|.:||.:.|.|::.:..|:::.      .:..|
Human   159 LYIVINGGV------EETT--ELLKQ--RFDHIFYTGNTAVGKIVMEAAAKHLT------PVTLE 207

  Fly   334 GGGKNFHFVHSSAEPETAVACTIRAAFEYAGQKCSSCSMLYVPESLWQNHIREPLLEITASLV-- 396
            .|||:..::....:.:..........:...||.|.:...:....|| ||.|...:.|......
Human   208 LGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASL-QNQIVWKIKETVKEFYGE 271

  Fly   397 -VRQDATYCDSFCSAVINRRAYDRIYMWLRYIDQSPSCQILVGGSCDKRRGYYVDPTVVLVKDLD 460
             :::...|     ..:||.|.:.||...|.      ..:|..||..|:.. .|:.|||:...|..
Human   272 NIKESPDY-----ERIINLRHFKRILSLLE------GQKIAFGGETDEAT-RYIAPTVLTDVDPK 324

  Fly   461 NIICREELLAPILGVYVYPDHKLKETMEKVAQINHGLTGSVFAQDQNFIEEAYDAFRVNVGNLNV 525
            ..:.:||:..|||.  :.|...:.|.:..:.:....|...||:.:...|:...|  ..:.|.:..
Human   325 TKVMQEEIFGPILP--IVPVKNVDEAINFINEREKPLALYVFSHNHKLIKRMID--ETSSGGVTG 385

  Fly   526 NDKSTGLMVGQQPFGAGHMTGTSDKLGTPHSLLRWTSPQVIKESYKT 572
            ||......:...|||....:|    :|..|.          |.|:.|
Human   386 NDVIMHFTLNSFPFGGVGSSG----MGAYHG----------KHSFDT 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh2	NP_788705.1	ALDH-SF	50..570	CDD:448367	92/433 (21%)
ALDH3A2	NP_001026976.1	ALDH_F3AB	5..444	CDD:143450	94/437 (22%)