Protein Alignment P5CDh2 and ALDH3B1

DIOPT Version :9

• Sequence 1: NP_788705.1
• Gene: P5CDh2 / 32625
• FlyBaseID: FBgn0053092
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_000685.1
• Gene: ALDH3B1 / 221
• HGNCID: 410
• Length: 468
• Species: Homo sapiens
• Alignment Length: 470
• Identity: 114/470 - (24%)
• Similarity: 191/470 - (40%)
• Gaps: 109/470 - (23%)

  Fly   154 AGRYR-YNIIAATMLGQGKTLRQ-----------------AEMDVAELVDFMRINPVFLRELANY 200
            |||.| ....||.:.|.|:.|::                 .|.:|:|:........:.||.|..:
Human    17 AGRTRPAEFRAAQLQGLGRFLQENKQLLHDALAQDLHKSAFESEVSEVAISQGEVTLALRNLRAW 81

  Fly   201 EPIRDIQNNCRNSMRLRGLS----GFVAAISPFNFTGIAANLAYTPAL----MGNSVIWKPSDSA 257
            .....:..|....:....:.    |.|..|:|:|:   ..||...|.:    .||.|:.|||:
Human    82 MKDERVPKNLATQLDSAFIRKEPFGLVLIIAPWNY---PLNLTLVPLVGALAAGNCVVLKPSE-- 141

  Fly   258 ILSNYFVFKALREAGVPDGVVNFVPAEETTFASVVTQHPKLAG---------INFTGTSTVLKVL 313
            |..|  |.|.|.|. :|..|      :::.|| ||...|:..|         |.|||:..|.|::
Human   142 ISKN--VEKILAEV-LPQYV------DQSCFA-VVLGGPQETGQLLEHRFDYIFFTGSPRVGKIV 196

  Fly   314 WQLVAQNINFYQNYPRLVGEGGGKNFHFVHSSAEPETAVACTIRAAFEY--AGQKCSS-----CS 371
            ....|:::.      .:..|.||||..:|..:.:|:| ||..: |.|.|  |||.|.:     ||
Human   197 MTAAAKHLT------PVTLELGGKNPCYVDDNCDPQT-VANRV-AWFRYFNAGQTCVAPDYVLCS 253

  Fly   372 MLYVPESLWQNHIREPLLEITASLVVRQDATYCDSFCSA-----VINRRAYDRIYMWLRYIDQSP 431
                ||      ::|.||....|.:.|   .|.|...|:     :||::.:.|:...|
Human   254 ----PE------MQERLLPALQSTITR---FYGDDPQSSPNLGRIINQKQFQRLRALL------- 298

  Fly   432 SC-QILVGGSCDKRRGYYVDPTVVL-VKDLDNIICREELLAPILGVYVYPDHKLKETMEKVAQIN 494
            .| ::.:||..|: ...|:.|||:: |::::.:: :||:..|||.:...  ..|.|.:|.:.:..
Human   299 GCGRVAIGGQSDE-SDRYIAPTVLVDVQEMEPVM-QEEIFGPILPIVNV--QSLDEAIEFINRRE 359

  Fly   495 HGLTGSVFAQDQNFIEEAYDAFRVNVGNLNVNDKSTGLMVGQQPFGAGHMTGTSDKLGTPHSLLR 559
            ..|....|:.....::....  :.:.|....||....:.:...|||....:|    :|..|....
Human   360 KPLALYAFSNSSQVVKRVLT--QTSSGGFCGNDGFMHMTLASLPFGGVGASG----MGRYHGKFS 418

  Fly   560 WTSPQVIKESYKTHR 574
            :       :::..||
Human   419 F-------DTFSHHR 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh2	NP_788705.1	ALDH-SF	50..570	CDD:299846	112/464 (24%)
ALDH3B1	NP_000685.1	ALDH_F3AB	6..447	CDD:143450	114/470 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900