Protein Alignment P5CDh2 and ALDH1A3

DIOPT Version :9

• Sequence 1: NP_788705.1
• Gene: P5CDh2 / 32625
• FlyBaseID: FBgn0053092
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_000684.2
• Gene: ALDH1A3 / 220
• HGNCID: 409
• Length: 512
• Species: Homo sapiens
• Alignment Length: 478
• Identity: 120/478 - (25%)
• Similarity: 218/478 - (45%)
• Gaps: 80/478 - (16%)

  Fly   124 IDKSVE-AQVKWDKVRLSDRIDIWERAAML-----IAGRYRYNIIAATMLGQGKTLRQA-EMDVA 181
            :||:|| |||.:.:.....|:|...|..:|     :..|.|..:.|...:..||....| .:|:.
Human    71 VDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLE 135

  Fly   182 ELVDFMRI-----------------NPV-FLRELANYEPIRDIQNNCRNSMRLRGLSGFVAAISP 228
            ..:..:|.                 |.| |.|    :|||                 |...||:|
Human   136 GCIRTLRYFAGWADKIQGKTIPTDDNVVCFTR----HEPI-----------------GVCGAITP 179

  Fly   229 FNFTGIAANLAYTPAL-MGNSVIWKPSDSAILSNYFVFKALREAGVPDGVVNFVPAEETTFASVV 292
            :||..:.......||| .||:::.||::...|:..::...::|||.|.||||.||....|..:.:
Human   180 WNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAI 244

  Fly   293 TQHPKLAGINFTGTSTVLKVLWQLVAQNINFYQNYPRLVGEGGGKNFHFVHSSAEPETAVACTIR 357
            :.||::..|.|||::.|.|::.:..:::     |..|:..|.||||...|.:.|:.:.||.|..:
Human   245 SSHPQINKIAFTGSTEVGKLVKEAASRS-----NLKRVTLELGGKNPCIVCADADLDLAVECAHQ 304

  Fly   358 AAFEYAGQKCSSCSMLYVPESLWQNHIREPLLEITASLVVRQDATYCDSF-----CSAVINRRAY 417
            ..|...||.|::.|.::|.|.::...:|.       |:...:.....|.|     ....|:::.:
Human   305 GVFFNQGQCCTAASRVFVEEQVYSEFVRR-------SVEYAKKRPVGDPFDVKTEQGPQIDQKQF 362

  Fly   418 DRIYMWLRYID--QSPSCQILVGGSCDKRRGYYVDPTVVLVKDLDNI-ICREELLAPILGVYVYP 479
            |:|   |..|:  :....::..|||..:.:|.::.|| |..:..||: |.:||:..|:..:..:
Human   363 DKI---LELIESGKKEGAKLECGGSAMEDKGLFIKPT-VFSEVTDNMRIAKEEIFGPVQPILKF- 422

  Fly   480 DHKLKETMEKVAQINHGLTGSVFAQDQNFIEEAYD-AFRVNVGNLNVNDKSTGLMVGQQPFGAGH 543
             ..::|.:::....::|||.:||.::   :::|.. |..:..|.:.:|  ....:..|.|||...
Human   423 -KSIEEVIKRANSTDYGLTAAVFTKN---LDKALKLASALESGTVWIN--CYNALYAQAPFGGFK 481

  Fly   544 MTGTSDKLGTPHSLLRWTSPQVI 566
            |:|...:|| .::|..:|..:.:
Human   482 MSGNGRELG-EYALAEYTEVKTV 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh2	NP_788705.1	ALDH-SF	50..570	CDD:299846	120/478 (25%)
ALDH1A3	NP_000684.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22
		ALDH_F1AB_F2_RALDH1	26..506	CDD:143459	120/478 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810