Protein Alignment P5CDh2 and ALDH3A1

DIOPT Version :10

• Sequence 1: NP_788705.1
• Gene: P5CDh2 / 32625
• FlyBaseID: FBgn0053092
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: XP_047291551.1
• Gene: ALDH3A1 / 218
• HGNCID: 405
• Length: 570
• Species: Homo sapiens
• Alignment Length: 357
• Identity: 78/357 - (21%)
• Similarity: 146/357 - (40%)
• Gaps: 67/357 - (18%)

  Fly   246 GNSVIWKPSD---------SAILSNYF---VFKALREAGVPDGVVNFVPAEETTFASVVTQHPKL 298
            ||||:.|||:         :.|:..|.   ::..: ..|||         |.|........|
Human   249 GNSVVLKPSELSENMASLLATIIPQYLDKDLYPVI-NGGVP---------ETTELLKERFDH--- 300

  Fly   299 AGINFTGTSTVLKVLWQLVAQNINFYQNYPRLVGEGGGKNFHFVHSSAEPETAVACTIRAAFEYA 363
              |.:||::.|.|::....|:::.      .:..|.|||:..:|..:.:.:.|........|..:
Human   301 --ILYTGSTGVGKIIMTAAAKHLT------PVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNS 357

  Fly   364 GQKCSSCSMLYVPESLWQNHIREPLLEITASLVVRQDATYCDSFCSAVINRRAYDRIYMWLRYID 428
            ||.|.:...:....|: ||.|.|.|.: :......:||.....: ..:|:.|.:.|:   :..|:
Human   358 GQTCVAPDYILCDPSI-QNQIVEKLKK-SLKEFYGEDAKKSRDY-GRIISARHFQRV---MGLIE 416

  Fly   429 QSPSCQILVGGSCDKRRGYYVDPTVVLVKDLDNIICREELLAPILGVYVYPDHKLKETMEKVAQI 493
            ..   ::..||:.|... .|:.||::...|..:.:.:||:..|:|.:...  ..|:|.::.:.|.
Human   417 GQ---KVAYGGTGDAAT-RYIAPTILTDVDPQSPVMQEEIFGPVLPIVCV--RSLEEAIQFINQR 475

  Fly   494 NHGLTGSVFAQDQNFIEEAYDAFRVNVGNLNVNDKSTGLMVGQQPFGAGHMTGTSDKLGTPHSLL 558
            ...|...:|:.:...|::.  ....:.|.:..||....:.:...|||....:|    :|:.|.
Human   476 EKPLALYMFSSNDKVIKKM--IAETSSGGVAANDVIVHITLHSLPFGGVGNSG----MGSYHG-- 532

  Fly   559 RWTSPQVIKESYKT--HRN--IFYPYMQINDQ 586
                    |:|::|  ||.  :..|.|  ||:
Human   533 --------KKSFETFSHRRSCLVRPLM--NDE 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh2	NP_788705.1	ALDH-SF	50..570	CDD:448367	70/335 (21%)
ALDH3A1	XP_047291551.1	ALDH-SF	<248..564	CDD:448367	78/357 (22%)