Protein Alignment P5CDh2 and alh-6

DIOPT Version :10

• Sequence 1: NP_788705.1
• Gene: P5CDh2 / 32625
• FlyBaseID: FBgn0053092
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_493946.1
• Gene: alh-6 / 173510
• WormBaseID: WBGene00000112
• Length: 563
• Species: Caenorhabditis elegans
• Alignment Length: 576
• Identity: 246/576 - (42%)
• Similarity: 355/576 - (61%)
• Gaps: 32/576 - (5%)

  Fly    16 ILPRLEASVKGGLVSVRSTSKRPELSEHFTLDEMVANEKLLQYDEGSKERTELETALLGVLNRVE 80
            |..:..||...||.|.....|:             .||.:|:|.:|||||.:||.||......:.
 Worm    11 ITQKCAASTYSGLTSADFLKKK-------------TNEPILEYRKGSKERQDLEAALAFYSKNIT 62

  Fly    81 HVPIVINGQEFQAKEDFQQVLPYDIQQPIAHYGHAHRVLIQMAIDKSVEAQVKWDKVRLSDRIDI 145
            .||:.|..::...|.:.:||:|.|.:..:|.|.:|....||.|||.:::|:..|::..|.:|.:|
 Worm    63 EVPLRIGDKKITNKLEQKQVIPSDHRSTLAKYTYATGEQIQEAIDVALQARGAWERKPLKERAEI 127

  Fly   146 WERAAMLIAGRYRYNIIAATMLGQGKTLRQAEMDVA-ELVDFMRINPVFLRELANYEPIRDIQNN 209
            ..|||.|.||:||..:.|:|||||||.:.|||:|.| ||:||.|.|.||..||.:||||.  ...
 Worm   128 LLRAADLAAGKYRMKLNASTMLGQGKNIIQAEIDAACELIDFFRFNAVFAMELEHYEPIS--TKI 190

  Fly   210 CRNSMRLRGLSGFVAAISPFNFTGIAANLAYTPALMGNSVIWKPSDSAILSNYFVFKALREAGVP 274
            .:|:|:.||:.||||||:|||||.|..||...||||||..:||||::|:||||.:::.|.|||:|
 Worm   191 TKNTMQFRGMEGFVAAIAPFNFTAIGGNLPTAPALMGNVSLWKPSNTAVLSNYIIYELLEEAGMP 255

  Fly   275 DGVVNFVPAEETTFASVVTQHPKLAGINFTGTSTVLKVLWQLVAQNINFYQNYPRLVGEGGGKNF 339
            .|:::|:|::...|..|:|..|.|:.:||||:....|.:|:.||:|::.|..:|:|:||.|||||
 Worm   256 PGILSFLPSDGPVFGDVITASPHLSAVNFTGSVPTFKTIWRKVAENLDNYVTFPKLIGECGGKNF 320

  Fly   340 HFVHSSAEPETAVACTIRAAFEYAGQKCSSCSMLYVPESLWQNHIREPLLEITASLV---VRQDA 401
            ||||.||..:...|.|.|:|:||:|||||:||.:|.|:|:|.. |.|.:..|...:.   ||..:
 Worm   321 HFVHPSAHVDAVAAGTARSAWEYSGQKCSACSRMYAPKSIWPK-ILEKISAIHKEIKLGDVRDGS 384

  Fly   402 TYCDSFCSAVINRRAYDRIYMWLRYID----QSPSCQILVGGSCDKRRGYYVDPTVVLVKDLDNI 462
            .    |.||||:.:|:.|:   ..|||    .:....:::||.||.:.||:::||::.|.|..:.
 Worm   385 V----FLSAVIDDKAFARL---KAYIDFAKTGADGANVVLGGKCDDKTGYFIEPTLITVTDPKSK 442

  Fly   463 ICREELLAPILGVYVYPDHKLKETMEKVAQIN-HGLTGSVFAQDQNFIEEAYDAFRVNVGNLNVN 526
            :..||:..|::.|.||.|.|:.|.:..|.... :||||:||:||:.|:..|.|..|..|||:.:|
 Worm   443 LLTEEMFGPVVTVLVYEDSKVDEVLATVKDATPYGLTGAVFSQDKEFLYRARDVLRDAVGNMYLN 507

  Fly   527 DKSTGLMVGQQPFGAGHMTGTSDKLGTPHSLLRWTSPQVIKESYKTHRNIFYPYMQ 582
            |||||.:|||||||...::||:||.|.||..||||||..|||:..:..:..||.|:
 Worm   508 DKSTGSIVGQQPFGGSRLSGTNDKAGGPHYGLRWTSPLTIKETSVSLTDWKYPSME 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh2	NP_788705.1	ALDH-SF	50..570	CDD:448367	236/528 (45%)
alh-6	NP_493946.1	ALDH_F4-17_P5CDH	34..552	CDD:143441	236/527 (45%)