DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gorab and Gorab

DIOPT Version :9

Sequence 1:	NP_788523.1	Gene:	Gorab / 326245	FlyBaseID:	FBgn0053052	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_849214.2	Gene:	Gorab / 98376	MGIID:	2138271	Length:	368	Species:	Mus musculus

Alignment Length:	343	Identity:	95/343 - (27%)
Similarity:	168/343 - (48%)	Gaps:	66/343 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTEKFNGFSHDEILKITGVKEGGVGKRPASLEAAKPALRIQPGIRRMPDKIFRQADQLRKQQQQQ 65
            |.:.:.|||.:|:.::...|:                 ..:|. ||:|.|..||..|..|...:|
Mouse     1 MAQDWAGFSEEELRRLKQNKD-----------------PFEPQ-RRIPVKKTRQQLQREKALLEQ 47

  Fly    66 PQQPIQKPDVAKKTKSGTATPTEKPPTPTPAAEDDVANGSLNLDRPLSDSLIEALYHGNATARDK 130
            .|            |.|                  :.:||.:|   |.:.|:.|... .|.::..
Mouse    48 SQ------------KLG------------------LQDGSASL---LPEQLLSAPKQ-RANSQKP 78

  Fly   131 KTPATYADAETTSTDDSSILKISGGDSQT----TSSTDDGSILPSTQDTSPRERLNTDSPFKGIS 191
            ::|:..|.:..|.|..|...|:.|..||.    ..::..|.  .|.:..:|:.....:.  |.:.
Mouse    79 RSPSPVAPSPLTPTSSSGDGKLPGVGSQPQEPGLENSHHGH--KSAEVRAPKPDCKVEK--KKME 139

  Fly   192 LKD------FEQHRRMIEEQNKQKKQMLYQAIEQHTQKTAAESRKIEEIRHELSKLESDLAVDVA 250
            |::      .:|.:|::||:||:||.:|.|||.:.::||.||:.|::.|:.||..|:..::.|:.
Mouse   140 LQEKSRWEVLQQEQRLMEEKNKRKKALLAQAIAERSKKTQAETIKLKRIQKELQALDDMVSADIG 204

  Fly   251 LLRKQIDNACIHFANVEKQYVKIEAQFLRAKIELHNASEKKELLTEHLCTVIAHNEDRKAQKLTE 315
            :||.:||.|.:.::...|::.:.||:::.||::|...:|.||.|||||||:|..||.|||:||.|
Mouse   205 ILRNRIDQASLEYSYARKRFDRAEAEYITAKLDLQRKTETKEQLTEHLCTIIQQNELRKAKKLEE 269

  Fly   316 LMQKVGLSPTDDCQPIDL 333
            |||::.:...::...:::
Mouse   270 LMQQLDVQADEEALQLEV 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gorab	NP_788523.1	Transcrip_act	<200..316	CDD:309879	50/115 (43%)
Gorab	NP_849214.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..43		6/41 (15%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	55..133		13/77 (17%)
		Transcrip_act	<154..275	CDD:282763	36/130 (28%)
		Necessary for interaction with RCHY1. /evidence=ECO:0000250	188..368		57/152 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	302..368		12/32 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836789
Domainoid	1	1.000	115	1.000	Domainoid score	I6027
eggNOG	1	0.900	-	-		E1_28Z6D
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4721
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007411
OrthoInspector	1	1.000	-	-		oto92391
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR21470
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5201
SonicParanoid	1	1.000	-	-		X5537
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.880