DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32985 and CG15695

DIOPT Version :9

Sequence 1:	NP_788013.2	Gene:	CG32985 / 326244	FlyBaseID:	FBgn0052985	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_650920.3	Gene:	CG15695 / 42468	FlyBaseID:	FBgn0038832	Length:	725	Species:	Drosophila melanogaster

Alignment Length:	603	Identity:	222/603 - (36%)
Similarity:	336/603 - (55%)	Gaps:	44/603 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 KLFYVESGKCKMRYVNPFNAEFLKINHPKAFIPCTNESDLISVHYDKILNQYVLHTNEEVLHELS 110
            |.::|.|.:|:|.:.|||......|....::|.|....|:|:|:|:...:.|.||.||
  Fly   154 KKYFVHSPQCQMSHPNPFANNIQHIYKKHSYIVCDKSRDMITVNYNVTDSTYRLHKNE------- 211

  Fly   111 ESKTNDFACFYQKIIYGQS--AEHYDGKGVKTKISQNHLVPLDVEGMLVECRTADEMRVLQRDAF 173
                |...||.|.:..|.|  |:|....|...:..|:.|||.:|..|:..||.....:|.|:|||
  Fly   212 ----NSTCCFKQILRAGTSANADHKYKLGPCVEFHQDFLVPTEVSAMITYCRRPPFDKVSQKDAF 272

  Fly   174 VFV-----QYKDP--PQNVKPVKKASVIMYGIDTVSRTNLRRMMPMVFEFLKSPGWYEMMGYNKV 231
            .||     |.::|  |...:|    ||:::|||::||.||...||.::|:|.:..|:|:.||||:
  Fly   273 SFVHPRKDQIENPTTPHRRRP----SVLLWGIDSISRMNLELTMPRMYEYLNNQHWFELQGYNKM 333

  Fly   232 ADNSFPNIFAMLTGFSPESAETQICNTDVDGCLDKIPFIWKDFKKDGYLTAYAEDEEHSNTFNYA 296
            .||:|||:.|:||||:...|..: |:.:....||..||||||||..||.||:|||....:||:|:
  Fly   334 GDNTFPNLMAVLTGFNKTYANAR-CHPEKVRGLDACPFIWKDFKDKGYTTAFAEDWSKFSTFDYS 397

  Fly   297 KPGFAVKPTDYYFRPFLTALENE-TFIQYCPGCVMKYCLGRRLASSYIFDYCRQF--MQRFVADR 358
            ..||...|||.|.||.:.|:|.| |.:|...   |.|||||:.||.||:|...||  :.|   :.
  Fly   398 SRGFFNPPTDVYGRPLVLAVEKELTILQRGQ---MPYCLGRKPASEYIYDMGVQFTMVNR---NS 456

  Fly   359 PIWGMFWTNHYSHDDLFMLSAMQHKILEDLLSFEKDGVFEHTIMIFFSDHGARFGPLMYTKEAFL 423
            ..:||||||.:||:|..|.|||..::::.:.:.:|:|:.::||:|||||||:|||||......|:
  Fly   457 TFFGMFWTNTFSHNDFSMPSAMDERMVKYMRTLDKNGIMDNTIIIFFSDHGSRFGPLRNLDSGFV 521

  Fly   424 EERLPMMFIYLPPWFRKKYPRYVEALAQNQNRLSSNFDLYNTLKHIINIEGLVEDTKWSYDCPQC 488
            |||||.::|.:|.|.|:|||:.:..|..|:|||:|.:|::.||:||:.::...:.......|..|
  Fly   522 EERLPFIYIRVPRWIREKYPKLLRNLQMNKNRLTSPYDIHATLRHILELDTPKDKLPRPDGCSSC 586

  Fly   489 QSLFYPLPESRSCSEAAIPEAYCTCHNYEEI-KEDQGTWRLANLVVDRMNKYLHYHNLQNLCSNL 552
            .|:|..:..||:||:|.|.:.:|.|:::.:: ..|.....::..:|:.:|:|:........||.|
  Fly   587 HSVFEEVDWSRNCSQAGIEDHWCACNSFSDVPTTDPSARSMSTQLVEAINEYVASKKGTKRCSRL 651

  Fly   553 TLRVINSTEVRMDDKDVDLANGMRHYHTKFQVHQNLAEFFATVLYDKQTEELQMNVELISRTNMY 617
            .|..|:|.:.|        .|..| |..:.......|.|.|||.:|...:.:...:..|||.:.|
  Fly   652 KLNRISSVQRR--------GNSNR-YLIQLMAQPGDALFEATVDWDASAQRIPAQMPSISRLDTY 707

  Fly   618 GTDSECVNNKIQKLYCVC 635
            ...|.|.:.|..|.||:|
  Fly   708 AAKSRCSSVKETKKYCIC 725

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32985	NP_788013.2	DUF229	72..554	CDD:308570	189/494 (38%)
CG15695	NP_650920.3	DUF229	180..656	CDD:281053	190/497 (38%)
CG15695	NP_650920.3	ALP_like	293..571	CDD:293745	132/288 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469426
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG27040
OrthoDB	1	1.010	-	-		D31599at6960
OrthoFinder	1	1.000	-	-		FOG0005924
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10974
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	5.050