Protein Alignment Pp2B-14D and CMP2

DIOPT Version :9

• Sequence 1: NP_001245715.1
• Gene: Pp2B-14D / 32624
• FlyBaseID: FBgn0011826
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_013655.1
• Gene: CMP2 / 854946
• SGDID: S000004521
• Length: 604
• Species: Saccharomyces cerevisiae
• Alignment Length: 575
• Identity: 283/575 - (49%)
• Similarity: 372/575 - (64%)
• Gaps: 74/575 - (12%)

  Fly    28 TDANSTASNNNNNSSSTAAAGNNSDNSSPTTGTGTGASTGKLHGGHTAVNTKERVVDSVPFPPSH 92
            |:...:::...::.:||.||.|     |..|.|....:...|..|. .|:|..|:::.||...||
Yeast    23 TERPQSSTTPIDSKASTVAAAN-----STATETSRDLTQYTLDDGR-VVSTNRRIMNKVPAITSH 81

  Fly    93 KLTLAEVFDQRTGKPNHELLKQHFILEGRIEEAPALKIIQDGAALLRQEKTMIDIEAPVTVCGDI 157
            ..|..|:| |..|.|.||.|:.||..||::..|.|.:|:.....|..:|..:|.:.||:||||||
Yeast    82 VPTDEELF-QPNGIPRHEFLRDHFKREGKLSAAQAARIVTLATELFSKEPNLISVPAPITVCGDI 145

  Fly   158 HGQFYDLMKLFEVGGSPASTKYLFLGDYVDRGYFSIECVLYLWSLKITYPQTLFLLRGNHECRHL 222
            |||::||:|||||||.||:|.|||||||||||.||.||::||:|||:.:....:||||||||:||
Yeast   146 HGQYFDLLKLFEVGGDPATTSYLFLGDYVDRGSFSFECLIYLYSLKLNFNDHFWLLRGNHECKHL 210

  Fly   223 TEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEIHELEDIRRLDRFKEP 287
            |.|||||.|...||:..:|:.|.::|:.||||||||.|:||||||:|||::.|:||..|:||:|.
Yeast   211 TSYFTFKNEMLHKYNLDIYEKCCESFNNLPLAALMNGQYLCVHGGISPELNSLQDINNLNRFREI 275

  Fly   288 PAFGPMCDLLWSDPLEDFG-------------NEK-----------NSDFYTHNSVRGCSYFYSY 328
            |:.|.||||||:||:|::.             |.|           :.|.:..||||||||.::|
Yeast   276 PSHGLMCDLLWADPIEEYDEVLDKDLTEEDIVNSKTMVPHHGKMAPSRDMFVPNSVRGCSYAFTY 340

  Fly   329 AACCDFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENN 393
            .|.|.|||...||||||||||||||||||:.::|.|||||:|:||||||||.||||||:||||||
Yeast   341 RAACHFLQETGLLSIIRAHEAQDAGYRMYKNTKTLGFPSLLTLFSAPNYLDTYNNKAAILKYENN 405

  Fly   394 VMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDEL--------------- 443
            ||||||||.:|||||||:|||||||||||||||||||||.:||||::|||
Yeast   406 VMNIRQFNMTPHPYWLPDFMDVFTWSLPFVGEKVTEMLVAILNICTEDELENDTPVIEELVGTDK 470

  Fly   444 ------MTEESEEP----------LSDDEAALRKEVIRNKIRAIGKMARVFSVLREESESVLQLK 492
                  .:|.:.:|          :.|||.  |::.:||||.|:.|::|::||||||:..|..||
Yeast   471 KLPQAGKSEATPQPATSASPKHASILDDEH--RRKALRNKILAVAKVSRMYSVLREETNKVQFLK 533

  Fly   493 GLTPTGALPLGALSGGKQSLKNAMQGFSPNHKITSFAEAKGLDAVNERMPPRRDQ 547
            ... :|.||.||||.|.:.|..|         :::|..|:..|.:||::||..|:
Yeast   534 DHN-SGVLPRGALSNGVKGLDEA---------LSTFERARKHDLINEKLPPSLDE 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pp2B-14D	NP_001245715.1	MPP_PP2B	107..411	CDD:277361	191/327 (58%)
CMP2	NP_013655.1	MPP_PP2B	95..423	CDD:277361	191/327 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	277	1.000	Domainoid score	I262
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	546	1.000	Inparanoid score	I170
Isobase	1	0.950	-	0.740582	Normalized mean entropy	S271
OMA	1	1.010	-	-		QHG53795
OrthoFinder	1	1.000	-	-		FOG0000983
OrthoInspector	1	1.000	-	-		mtm9223
orthoMCL	1	0.900	-	-		OOG6_100566
Panther	1	1.100	-	-	O	PTHR45673
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R954
SonicParanoid	1	1.000	-	-		X576
TreeFam	1	0.960	-	-
	14	13.810