Protein Alignment Pp2B-14D and PPH22

DIOPT Version :10

• Sequence 1: NP_523373.2
• Gene: Pp2B-14D / 32624
• FlyBaseID: FBgn0011826
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_010093.1
• Gene: PPH22 / 851339
• SGDID: S000002347
• Length: 377
• Species: Saccharomyces cerevisiae
• Alignment Length: 371
• Identity: 134/371 - (36%)
• Similarity: 195/371 - (52%)
• Gaps: 45/371 - (12%)

  Fly    48 GNNSDNSSPTTGTGTGASTGKLHGGHTAVNTKER--------VVDSVPFPPSHKLTLAEVFDQRT 104
            |::.|..|||......:..||       .|||.|        .::...|.|..    :.:.|.::
Yeast    11 GSDEDQLSPTLDEDMNSDDGK-------NNTKARSNDEDTDEELEDFNFKPGS----SGIADHKS 64

  Fly   105 GKP------NHELLKQ---HFILEGRIEEAPALKIIQDGAALLRQEKTMIDIEAPVTVCGDIHGQ 160
            .||      |...|.|   |......:.|....::.:....:|:.|:.:..|..|||:|||:|||
Yeast    65 SKPLKLTNTNINQLDQWIEHLSKCEPLSEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQ 129

  Fly   161 FYDLMKLFEVGGSPASTKYLFLGDYVDRGYFSIECVLYLWSLKITYPQTLFLLRGNHECRHLTEY 225
            |:||::||::||....|.|||:||||||||:|:|.|.||.::|:.||..:.:||||||.|.:|:.
Yeast   130 FHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQV 194

  Fly   226 FTFKQECKIKY-SERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEIHELEDIRRLDRFKEPPA 289
            :.|..||..|| |..|:....|.||..|:.||::.:..|:||||||.|..::.:|.|:|.:|.|.
Yeast   195 YGFYDECLRKYGSANVWKMFTDLFDYFPVTALVDNKIFCLHGGLSPMIETIDQVRDLNRIQEVPH 259

  Fly   290 FGPMCDLLWSDPLEDFGNEKNSDFYTHNSVRGCSYFYSYAACCDFLQNNNLLSIIRAHEAQDAGY 354
            .||||||||||| :|.|.       ...|.||..:.:.......|...|:|..|.|||:....||
Yeast   260 EGPMCDLLWSDP-DDRGG-------WGISPRGAGFTFGQDISEQFNHTNDLSLIARAHQLVMEGY 316

  Fly   355 RMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQF 400
            ....:.      :::||||||||.....|:||:::.:.|  :.|||
Yeast   317 SWSHQQ------NVVTIFSAPNYCYRCGNQAAIMEVDEN--HNRQF 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pp2B-14D	NP_523373.2	MPP_PP2B	107..411	CDD:277361	119/304 (39%)
PPH22	NP_010093.1	MPP_PP2A_PP4_PP6	78..360	CDD:277360	117/293 (40%)