Protein Alignment Pp2B-14D and PPP1CA

DIOPT Version :10

• Sequence 1: NP_523373.2
• Gene: Pp2B-14D / 32624
• FlyBaseID: FBgn0011826
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_001008709.1
• Gene: PPP1CA / 5499
• HGNCID: 9281
• Length: 341
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 109/260 - (41%)
• Similarity: 160/260 - (61%)
• Gaps: 19/260 - (7%)

  Fly   144 MIDIEAPVTVCGDIHGQFYDLMKLFEVGGSPASTKYLFLGDYVDRGYFSIECVLYLWSLKITYPQ 208
            ::::|||:.:|||||||:|||::|||.||.|..:.|||||||||||..|:|.:..|.:.||.||:
Human    63 LLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPE 127

  Fly   209 TLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEIH 273
            ..|||||||||..:...:.|..|||.:|:.:::....|.|:|||:||:::::..|.||||||::.
Human   128 NFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ 192

  Fly   274 ELEDIRRLDRFKEPPAFGPMCDLLWSDPLEDFGNEKNSDFYTHNSVRGCSYFYSYAACCDFLQNN 338
            .:|.|||:.|..:.|..|.:||||||||.:|......:|       ||.|:.:.......||..:
Human   193 SMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGEND-------RGVSFTFGAEVVAKFLHKH 250

  Fly   339 NLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCS 403
            :|..|.|||:..:.||..:.|.|      |:|:||||||...::|..|::..:..:|      ||
Human   251 DLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGAMMSVDETLM------CS 303

  Fly   404  403
            Human   304  303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pp2B-14D	NP_523373.2	MPP_PP2B	107..411	CDD:277361	109/260 (42%)
PPP1CA	NP_001008709.1	MPP_PP1_PPKL	8..309	CDD:277359	109/260 (42%)