DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pp2B-14D and rdgC

DIOPT Version :9

Sequence 1:	NP_001245715.1	Gene:	Pp2B-14D / 32624	FlyBaseID:	FBgn0011826	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster

Alignment Length:	353	Identity:	103/353 - (29%)
Similarity:	165/353 - (46%)	Gaps:	63/353 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 VNTKERVVDSVPFPPSHKLTLAEVFDQRTGKPNHELLKQHFILEGRIEEAPALKIIQDGAALLRQ 140
            ||.|    ..:|...:|...|.:||.::.|              .|:.......|:::.|..|:|
  Fly   177 VNAK----IELPIRKNHIDLLIDVFRKKRG--------------NRLHPKYVALILREAAKSLKQ 223

  Fly   141 ----EKTMIDIEAPVTVCGDIHGQFYDLMKLFEVGGSPASTK-YLFLGDYVDRGYFSIECVLYLW 200
                ......:...||||||:||:..||:.:....|.|:|:. |:|.||:||||...:|.:|.|.
  Fly   224 LPNISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLL 288

  Fly   201 SLKITYPQTLFLLRGNHECRHLTEYFTFKQECKIKY---SERVYDACMDAFDCLPLAALMNQQFL 262
            ||.:.:|..:||.|||||...:...:.|.:|.:.||   .:|:.....:.:..|||.:::|.:.|
  Fly   289 SLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKYPRNHKRILAFIDEVYRWLPLGSVLNSRVL 353

  Fly   263 CVHGGLSPEIHELEDIRRLDRFK-----EPP----------AFGPMCDLLWSDPLEDFGNEKNSD 312
            .||||.| :...|:.|:.:||.|     .||          .:..:.|::||||....|
  Fly   354 IVHGGFS-DSTSLDLIKSIDRGKYVSILRPPLTDGEPLDKTEWQQIFDIMWSDPQATMG------ 411

  Fly   313 FYTHNSVRGCSYFYSYAACCDFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNY 377
             ...|::||...::......:|||.:.|..:||:||.:..|:.....::      :||||||.||
  Fly   412 -CVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIRSHECKPNGHEFMHDNK------IITIFSASNY 469

  Fly   378 LDVYNNKAAVLKYENNVMNIRQFNCSPH 405
            ..:.:||.|.::..|.:|        ||
  Fly   470 YAIGSNKGAYIRLNNQLM--------PH 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp2B-14D	NP_001245715.1	MPP_PP2B	107..411	CDD:277361	94/322 (29%)
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	100/342 (29%)
		EFh	616..681	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438801
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930