Protein Alignment CG32750 and BTD

DIOPT Version :10

• Sequence 1: NP_727067.1
• Gene: CG32750 / 326238
• FlyBaseID: FBgn0052750
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_001268652.2
• Gene: BTD / 686
• HGNCID: 1122
• Length: 523
• Species: Homo sapiens
• Alignment Length: 539
• Identity: 147/539 - (27%)
• Similarity: 225/539 - (41%)
• Gaps: 104/539 - (19%)

  Fly    19 TDDNSV----ENKFYIAGVVEY------RPTFMGGTSE--QLLQANLAGY-LEIMASGNGTTDII 70
            |.:.||    |.::|:|.|.|:      .|..:....|  :|:..||..| .::|.:......||
Human    24 TGEESVADHHEAEYYVAAVYEHPSILSLNPLALISRQEALELMNQNLDIYEQQVMTAAQKDVQII 88

  Fly    71 VFPEATLNSV-ITLTAV---------PKFTEQSLC-EEQGDDDPEIAPFLRSLACAAREYGTYLV 124
            ||||..::.. .|.|::         |:....:.| |....:|.|:   |:.|:|.|.....:||
Human    89 VFPEDGIHGFNFTRTSIYPFLDFMPSPQVVRWNPCLEPHRFNDTEV---LQRLSCMAIRGDMFLV 150

  Fly   125 VNVKERVSEQC-TSDETCSSRGYSIHNTNVVFDRQGAVISRYRKWNLYLEPSTNRTESPEIATFT 188
            .|:..:  |.| :||..|...|....||||||...|.::.||||.|||.|.:.:.....::.||.
Human   151 ANLGTK--EPCHSSDPRCPKDGRYQFNTNVVFSNNGTLVDRYRKHNLYFEAAFDVPLKVDLITFD 213

  Fly   189 TDFNVTFGHFICFDMLFYTPAQDLVEQLGIRHVIVTKMFNSELPFLTASQFQQGWAWANRVNLLA 253
            |.|...||.|.|||:||:.||..::....::||:....:.::||.|.|.:.|:.:|.|..:|:||
Human   214 TPFAGRFGIFTCFDILFFDPAIRVLRDYKVKHVVYPTAWMNQLPLLAAIEIQKAFAVAFGINVLA 278

  Fly   254 SGGSLPQGGISGSGIYAGQQGALARLMITDELVGQRKLLLAKVPLDPEEPI----ATDEILEPEI 314
            :....|..|::||||:.    .|......|....:..|::|:|..:|...|    ||.| .:|..
Human   279 ANVHHPVLGMTGSGIHT----PLESFWYHDMENPKSHLIIAQVAKNPVGLIGAENATGE-TDPSH 338

  Fly   315 MTPVKL--------KLLQQPELKNFTTWE-----------------LPMVRGSSVDKRICQEDLC 354
            ...:|:        |..|:......|.|.                 |..|.|......:|...||
Human   339 SKFLKILSGDPYCEKDAQEVHCDEATKWNVNAPPTFHSEMMYDNFTLVPVWGKEGYLHVCSNGLC 403

  Fly   355 CEF---RVTWTLEDTQPEYNYRLGVWVGQRRYEEEQYSAIRLCGLFACKGASVESCGLVSEE--- 413
            |..   |.|.:.|      .|.|||:.|........|  |::|.|..|.|...::||....|
Human   404 CYLLYERPTLSKE------LYALGVFDGLHTVHGTYY--IQVCALVRCGGLGFDTCGQEITEATG 460

  Fly   414 --EVHLQDHRVVFTDLQILGEFVRRPRRLILPSTLS-SSSFYALQPSQLAWSMEELANVTRIKME 475
              |.||..:   |:...|...|:.....|.:|..|. .:..|.|:.|:|:
Human   461 IFEFHLWGN---FSTSYIFPLFLTSGMTLEVPDQLGWENDHYFLRKSRLS--------------- 507

  Fly   476 LRQPHSQLMTFAIYGNYFD 494
                 |.|:|.|:||..::
Human   508 -----SGLVTAALYGRLYE 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32750	NP_727067.1	biotinidase_like	29..322	CDD:143591	96/325 (30%)
		Vanin_C	320..495	CDD:465946	47/209 (22%)
BTD	NP_001268652.2	biotinidase_like	38..341	CDD:143591	95/312 (30%)
		Vanin_C	373..523	CDD:465946	43/180 (24%)