DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32750 and NitFhit

DIOPT Version :9

Sequence 1:	NP_727067.1	Gene:	CG32750 / 326238	FlyBaseID:	FBgn0052750	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_525122.1	Gene:	NitFhit / 38029	FlyBaseID:	FBgn0024945	Length:	460	Species:	Drosophila melanogaster

Alignment Length:	227	Identity:	45/227 - (19%)
Similarity:	83/227 - (36%)	Gaps:	70/227 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 MGGTSEQLLQANLAGYLEIMASGNGTTDIIVF-PEATLNSVITLTAVPKFTEQSLCEEQGDD--- 101
            |..||::  .|||:..:|::.........::| ||.                   |:..|:.
  Fly    40 MRSTSDK--AANLSQVIELVDRAKSQNACMLFLPEC-------------------CDFVGESRTQ 83

  Fly   102 --------DPEIAPFLRSLACAAREYGTYLVVNVKERVSEQCTSDETCSSRGYSIHNTNVVFDRQ 158
                    |.|:....|.||...:.:  ..:..|.||..::             |.|.:|:.:.:
  Fly    84 TIELSEGLDGELMAQYRELAKCNKIW--ISLGGVHERNDQK-------------IFNAHVLLNEK 133

  Fly   159 GAVISRYRKWNLYLEPSTNRTESPEIATFTTDFNV---------TFGHFICFDMLFYTPAQDLVE 214
            |.:.:.|||.::: :.:|......|..|.|..:.:         ..|..||:|:.|..||
  Fly   134 GELAAVYRKLHMF-DVTTKEVRLRESDTVTPGYCLERPVSTPVGQIGLQICYDLRFAEPA----- 192

  Fly   215 QLGIRHVIVTKMFNSELPFLTASQFQQGWA-W 245
                  |::.|:..:.|.:.:|..:..|.| |
  Fly   193 ------VLLRKLGANLLTYPSAFTYATGKAHW 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32750	NP_727067.1	biotinidase_like	29..322	CDD:143591	45/227 (20%)
NitFhit	NP_525122.1	nit	34..296	CDD:143596	45/227 (20%)
NitFhit	NP_525122.1	FHIT	317..436	CDD:238606
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0388
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900