Protein Alignment CG32750 and Vnn1

DIOPT Version :10

• Sequence 1: NP_727067.1
• Gene: CG32750 / 326238
• FlyBaseID: FBgn0052750
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_001020794.1
• Gene: Vnn1 / 29142
• RGDID: 1310075
• Length: 512
• Species: Rattus norvegicus
• Alignment Length: 550
• Identity: 141/550 - (25%)
• Similarity: 248/550 - (45%)
• Gaps: 82/550 - (14%)

  Fly     5 LRRFL-WLISFTL-VLTDDNSVENKFYIAGVVEY-----RPTFMGGTSEQ---LLQANLAGYLE- 58
            |.|:| |..:|:: .:...:|::.  ::|.|.|:     :.|.:..:..:   |:..|| ..||
  Rat     3 LSRWLAWAAAFSVFCVLKVSSLDT--FLAAVYEHAVILPKVTLLPVSHSEALALMNQNL-DLLEG 64

  Fly    59 -IMASGNGTTDIIVFPEATLNSVITLTAVPKFTEQSL---CEEQGD--------DDPE---IAPF 108
             |:::......|||.||..:..|       :||..::   .|:..|        |:||   ..|.
  Rat    65 AILSAAKQGAHIIVTPEDGIYGV-------QFTRDTIYPYLEDIPDPQVNWIPCDNPERFGSTPV 122

  Fly   109 LRSLACAAREYGTYLVVNVKERVSEQC-TSDETCSSRGYSIHNTNVVFDRQGAVISRYRKWNLYL 172
            ...|:|.|:....|:|.|:.::  :.| |||..|...|...:||:||||.:|.:::||.|.||::
  Rat   123 QERLSCLAKNNSIYVVANMGDK--KPCNTSDSHCPPDGRFQYNTDVVFDSRGKLVARYHKQNLFM 185

  Fly   173 -EPSTNRTESPEIATFTTDFNVTFGHFICFDMLFYTPAQDLVEQLGIRHVIVTKMFNSELPFLTA 236
             |...|....||:.||.|.|. .||.|.|||:||:.||..||.:..:..::....:...||.|.|
  Rat   186 GEEQFNAPPEPEVVTFDTPFG-KFGIFTCFDILFHDPAVTLVTEFQVDTILFPTAWMDVLPHLAA 249

  Fly   237 SQFQQGWAWANRVNLLASGGSLPQGGISGSGIYAGQQGALARLMITDELVGQRKLLLAKVPLDPE 301
            .:|...||....||.||:...:|...::||||||...   .|....|....:.|||||::...|.
  Rat   250 IEFHSAWAIGMGVNFLAANLHIPLRRMTGSGIYAPDS---PRAFHYDRKTQEGKLLLAQLDSHPS 311

  Fly   302 EPIATDEILEPEIMTPVKLKLLQQPELKNFTTWE---LPMVRGSSVDKRICQEDLCCEFRVTWTL 363
            .    ..:......:.|:....::.|.::|..::   ...::|.:.:..:||.||||  .:::.:
  Rat   312 H----SPVNWTSYASSVEAPPTEKEEFRSFVFFDEFTFVELKGITGNYTVCQNDLCC--HLSYQM 370

  Fly   364 EDTQPEYNYRLGVWVGQRRYEEEQYSAIRLCGLFACKGASVESCGLVSEEEVHLQDHRVVFTDLQ 428
            .:.:.:..|.||.:.|....|.:.:  :::|.|..||..::.:||    ..|.....|  |....
  Rat   371 SEKRADEVYALGAFDGLHTVEGQYH--LQICILLKCKTTNLRTCG----SSVDTASTR--FEMFS 427

  Fly   429 ILGEFVRR---PRRLILPSTLSSSSFYALQPSQLAWSMEELANVTRIKMELRQPHSQLMTFAIYG 490
            :.|.|..|   |..|:....|:...|..|...:|              :.|:.....::|..::|
  Rat   428 LSGTFGTRYVFPEVLLSEVKLAPGEFQVLSDGRL--------------VSLKPTSGPVLTVGLFG 478

  Fly   491 NYFD-EYANGGAGRL---GTLLFLLITPLI 516
            ..:: ::|:..:..|   ..::.|::.|:|
  Rat   479 RLYEKDWASNASSDLIAHSLIIMLILAPII 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32750	NP_727067.1	biotinidase_like	29..322	CDD:143591	95/318 (30%)
		Vanin_C	320..495	CDD:465946	35/181 (19%)
Vnn1	NP_001020794.1	biotinidase_like	27..324	CDD:143591	94/314 (30%)
		Vanin_C	338..484	CDD:465946	33/169 (20%)