DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32750 and btd

DIOPT Version :9

Sequence 1:	NP_727067.1	Gene:	CG32750 / 326238	FlyBaseID:	FBgn0052750	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	XP_002932835.2	Gene:	btd / 100489727	XenbaseID:	XB-GENE-982203	Length:	507	Species:	Xenopus tropicalis

Alignment Length:	542	Identity:	145/542 - (26%)
Similarity:	226/542 - (41%)	Gaps:	102/542 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LWLISFTLVLTDDNSVENKFYIAGVVEYRPTFMGGTSE--------QLLQANLAGY-LEIMASGN 64
            :::....:.|.:.:||  .:|.|.|.|:.......:|.        :.:..||..| :::..:..
Frog    10 IYIFCCLVPLLNGDSV--AYYTAAVYEHHAILNQNSSTLTDRKSALEFMFQNLDIYEIQVATAAE 72

  Fly    65 GTTDIIVFPEATLNSVITLTAVPKFTEQSL-----------------CEEQGD-DDPEIAPFLRS 111
            ....||||||..::..       .:|.||:                 |:|... .|.|:   |:.
Frog    73 RGAQIIVFPEDGIHGF-------NYTRQSIYPYLDFLPPSHLLPWNPCQEPDRFSDTEV---LQR 127

  Fly   112 LACAAREYGTYLVVNVKERVSEQCTSDE-TCSSRGYSIHNTNVVFDRQGAVISRYRKWNLYLEPS 175
            |:|.|.:...|||.|:..:|  .|.... .|....|.. ||||||...|.:::.|.|.|||.|..
Frog   128 LSCMAVKGRMYLVANLGTKV--PCEHHHFRCPDGRYQF-NTNVVFSSNGTLVASYFKQNLYFEYG 189

  Fly   176 TNRTESPEIATFTTDFNVTFGHFICFDMLFYTPAQDLVEQLGIRHVIVTKMFNSELPFLTASQFQ 240
            .:.....:...|.|.|...||...|||:|||.||..|||...::|::....:.::||.|:|.|.|
Frog   190 FDIPPKAQHVVFNTPFASKFGLITCFDILFYKPAVSLVESHMVKHILYPTAWMNQLPLLSAIQIQ 254

  Fly   241 QGWAWANRVNLLASGGSLPQGGISGSGIYAGQQGALARLMITDELVGQRKLLLAKVPLDPEEPIA 305
            :.:|.|..:||||:.....:.|::|||||:..|......|.:|    ..|||:.|||:|| .|..
Frog   255 RAFASAFGINLLAANIHHTKLGMTGSGIYSPSQSYFYFDMTSD----NGKLLIGKVPVDP-LPAG 314

  Fly   306 TD------------------EILEPEIMTPVKLKLLQ--------QPEL--KNFTTWELPMVRGS 342
            .:                  ::.|.:.....:..||:        |.|:  .|||...|..|.|:
Frog   315 HNAQVSFGSQNINRLHWLHGDVCELDRAEHCRASLLRHQLPPSEFQAEMMYDNFTFIPLAAVEGA 379

  Fly   343 SVDKRICQEDLCCEFRVTWTLEDTQPEYNYRLGVWVGQRRYEEEQYSAIRLCGLFACKGASVESC 407
               .::| ...||....|.|||..:   .|.||::.|........|  :::|.|..|.|...|:|
Frog   380 ---VKVC-SSFCCYLNYTKTLESDE---FYALGIFDGLHTVHGTYY--LQICALVKCGGLEPETC 435

  Fly   408 GLVSEEEVHLQDHRVVFTDLQILGEFVRRPRRLILPSTLSSSSFYALQPSQLAWSMEELANVTRI 472
            |    :||   .......:.|:.|.|..:.   |.|..|:|.....|..|   |..::    :..
Frog   436 G----QEV---TEAGTIINFQLWGNFTTKH---IFPMLLTSGVTLHLPDS---WGWKD----SHC 483

  Fly   473 KMELRQPHSQLMTFAIYGNYFD 494
            .|:.....|.|:|.|:||..::
Frog   484 YMKNENMSSGLVTAALYGRLYN 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32750	NP_727067.1	biotinidase_like	29..322	CDD:143591	94/338 (28%)
btd	XP_002932835.2	biotinidase_like	28..310	CDD:143591	90/298 (30%)
btd	XP_002932835.2	Vanin_C	359..507	CDD:408788	46/173 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	92	1.000	Domainoid score	I7475
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	153	1.000	Inparanoid score	I4227
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1276751at2759
OrthoFinder	1	1.000	-	-		FOG0001380
OrthoInspector	1	1.000	-	-		mtm9511
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X969
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060