DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ubi-p5E and UBL4A

DIOPT Version :10

Sequence 1:NP_727078.1 Gene:Ubi-p5E / 326237 FlyBaseID:FBgn0086558 Length:534 Species:Drosophila melanogaster
Sequence 2:NP_055050.1 Gene:UBL4A / 8266 HGNCID:12505 Length:157 Species:Homo sapiens


Alignment Length:141 Identity:44/141 - (31%)
Similarity:69/141 - (48%) Gaps:21/141 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES 65
            ||:.||.|.|:..:|:|...:.:..:|..:.:|..:|..||||:|.||.|.||:.||||:|...|
Human     1 MQLTVKALQGRECSLQVPEDELVSTLKQLVSEKLNVPVRQQRLLFKGKALADGKRLSDYSIGPNS 65

  Fly    66 TLHLVLRLRGGMQIFVKTL------TGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGK 124
            .|:||          ||.|      .|:...|...|...:..:.:|:..:.....|..|::   :
Human    66 KLNLV----------VKPLEKVLLEEGEAQRLADSPPPQVWQLISKVLARHFSAADASRVL---E 117

  Fly   125 QLEDG--RTLS 133
            ||:..  |:||
Human   118 QLQRDYERSLS 128

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ubi-p5ENP_727078.1 Ubl_ubiquitin 1..76 CDD:340501 30/74 (41%)
Ubl_ubiquitin 77..152 CDD:340501 14/65 (22%)
Ubl_ubiquitin 153..228 CDD:340501
Ubl_ubiquitin 229..304 CDD:340501
Ubl_ubiquitin 305..380 CDD:340501
Ubl_ubiquitin 381..456 CDD:340501
Ubl_ubiquitin 457..532 CDD:340501
UBL4ANP_055050.1 Ubl_UBL4A_like 1..72 CDD:340505 30/80 (38%)
Tugs 96..142 CDD:465528 8/36 (22%)
Required and sufficient for interaction with BAG6. /evidence=ECO:0000269|PubMed:25535373, ECO:0000269|PubMed:25713138 96..138 8/36 (22%)
Blue background indicates that the domain is not in the aligned region.

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