DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Ubi-p5E and UBQ8

DIOPT Version :9

Sequence 1:NP_001284937.1 Gene:Ubi-p5E / 326237 FlyBaseID:FBgn0086558 Length:534 Species:Drosophila melanogaster
Sequence 2:NP_001319513.1 Gene:UBQ8 / 820137 AraportID:AT3G09790 Length:631 Species:Arabidopsis thaliana


Alignment Length:627 Identity:409/627 - (65%)
Similarity:448/627 - (71%) Gaps:101/627 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES 65
            :||:.||||.|||||:||.||:|.|||||||:|||||.|||||||||||||||.||:||||||||
plant     3 IQIYAKTLTEKTITLDVETSDSIHNVKAKIQNKEGIPLDQQRLIFAGKQLEDGLTLADYNIQKES 67

  Fly    66 TLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGR 130
            ||||||||||||||||:|||||||||||:.||||:||||||||||||.|.|||||||||||||||
plant    68 TLHLVLRLRGGMQIFVQTLTGKTITLEVKSSDTIDNVKAKIQDKEGILPRQQRLIFAGKQLEDGR 132

  Fly   131 TLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGK-----TITLEVEPSDTIENVKAKIQDKEGIPP 190
            ||:||||||||||||||||.|||||||.|.:||     |:||:||.|||||||||||||:||:.|
plant   133 TLADYNIQKESTLHLVLRLCGGMQIFVSTFSGKNFTSDTLTLKVESSDTIENVKAKIQDREGLRP 197

  Fly   191 DQQ-------------------------------------------------------------- 193
            |.|                                                              
plant   198 DHQRLIFHGEELFTEDNRTLADYGIRNRSTLCLALRLRGDMYIFVKNLPYNSFTGENFILEVESS 262

  Fly   194 ---------------------RLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLT 237
                                 |||||||.||.||||:.|||||.|||:||.|.|.||||||||||
plant   263 DTIDNVKAKLQDKERIPMDLHRLIFAGKPLEGGRTLAHYNIQKGSTLYLVTRFRCGMQIFVKTLT 327

  Fly   238 GKTITLEVEPSDTIENVKAKIQDKEGI--PPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLR 300
            .|.|.||||..||||||||.:||||||  .|:.|||||.||:|:||.||:||:||||||||||| 
plant   328 RKRINLEVESWDTIENVKAMVQDKEGIQPQPNLQRLIFLGKELKDGCTLADYSIQKESTLHLVL- 391

  Fly   301 LRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNI 365
               |||||||...||.|||||..||||::||||||||.|.|||||.|:|.|.||:|||||.||||
plant   392 ---GMQIFVKLFGGKIITLEVLSSDTIKSVKAKIQDKVGSPPDQQILLFRGGQLQDGRTLGDYNI 453

  Fly   366 QKESTLHLVLRLRGGMQIFVKTL-------TGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRL 423
            :.||||||...:|.||||||||.       |.||||||||.||||:|||.|||.|.|||.|:|||
plant   454 RNESTLHLFFHIRHGMQIFVKTFSFSGETPTCKTITLEVESSDTIDNVKVKIQHKVGIPLDRQRL 518

  Fly   424 IFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQD 488
            ||.|:.|...|||.||||||.||:|.:...|||||||:||||||||.||||.||||.|||.|||.
plant   519 IFGGRVLVGSRTLLDYNIQKGSTIHQLFLQRGGMQIFIKTLTGKTIILEVESSDTIANVKEKIQV 583

  Fly   489 KEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLR 530
            ||||.||||.|||.|:|||||.||.||:|.|:|||:||||||
plant   584 KEGIKPDQQMLIFFGQQLEDGVTLGDYDIHKKSTLYLVLRLR 625

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ubi-p5ENP_001284937.1 Ubiquitin 1..76 CDD:176398 62/74 (84%)
UBQ 1..72 CDD:214563 58/70 (83%)
Ubiquitin 77..152 CDD:176398 66/74 (89%)
UBQ 77..148 CDD:214563 63/70 (90%)
Ubiquitin 153..228 CDD:176398 56/162 (35%)
UBQ 153..224 CDD:214563 54/158 (34%)
Ubiquitin 229..304 CDD:176398 55/76 (72%)
UBQ 229..300 CDD:214563 54/72 (75%)
Ubiquitin 305..380 CDD:176398 52/74 (70%)
UBQ 305..376 CDD:214563 51/70 (73%)
Ubiquitin 381..456 CDD:176398 51/81 (63%)
UBQ 381..452 CDD:214563 50/77 (65%)
Ubiquitin 457..532 CDD:176398 58/74 (78%)
UBQ 457..528 CDD:214563 54/70 (77%)
UBQ8NP_001319513.1 Ubl_ubiquitin 3..78 CDD:340501 62/74 (84%)
Ubl_ubiquitin 79..154 CDD:340501 66/74 (89%)
Ubiquitin_like_fold 155..237 CDD:391949 31/81 (38%)
Ubiquitin_like_fold 238..318 CDD:391949 25/79 (32%)
Ubiquitin_like_fold 319..391 CDD:391949 53/71 (75%)
Ubiquitin_like_fold 393..468 CDD:391949 52/74 (70%)
Ubiquitin_like_fold 469..551 CDD:391949 51/81 (63%)
Ubiquitin_like_fold 552..625 CDD:391949 56/72 (78%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5272
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53680
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000540
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100667
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
65.680

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