DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubi-p5E and Ubl4a

DIOPT Version :9

Sequence 1:	NP_001284937.1	Gene:	Ubi-p5E / 326237	FlyBaseID:	FBgn0086558	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	NP_663380.1	Gene:	Ubl4a / 27643	MGIID:	95049	Length:	157	Species:	Mus musculus

Alignment Length:	142	Identity:	45/142 - (31%)
Similarity:	67/142 - (47%)	Gaps:	24/142 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES 65
            ||:.||.|.|:..:|:|...:.:..:|..:.||..:|..||||:|.||.|.|.:.||||||...|
Mouse     1 MQLTVKALQGRECSLQVAEDELVSTLKHLVSDKLNVPVRQQRLLFKGKALADEKRLSDYNIGPNS 65

  Fly    66 TLHLVLRLRGGMQIFVKTL------TGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGK 124
            .|:||          ||.|      .|....|...|:..|..:.:|:..:.....|..|::   :
Mouse    66 KLNLV----------VKPLEKVLLEEGSAHRLVDSPATPIWQLISKVLARHFSVADASRVL---E 117

  Fly   125 QLEDGRTLSDYN 136
            ||:     .||:
Mouse   118 QLQ-----RDYD 124

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubi-p5E	NP_001284937.1	Ubiquitin	1..76	CDD:176398	31/74 (42%)
		UBQ	1..72	CDD:214563	31/70 (44%)
		Ubiquitin	77..152	CDD:176398	14/66 (21%)
		UBQ	77..148	CDD:214563	14/66 (21%)
		Ubiquitin	153..228	CDD:176398
		UBQ	153..224	CDD:214563
		Ubiquitin	229..304	CDD:176398
		UBQ	229..300	CDD:214563
		Ubiquitin	305..380	CDD:176398
		UBQ	305..376	CDD:214563
		Ubiquitin	381..456	CDD:176398
		UBQ	381..452	CDD:214563
		Ubiquitin	457..532	CDD:176398
		UBQ	457..528	CDD:214563
Ubl4a	NP_663380.1	Ubl_UBL4A_like	1..72	CDD:340505	31/80 (39%)
		Tugs	96..142	CDD:375372	7/37 (19%)
		Required and sufficient for interaction with BAG6. /evidence=ECO:0000250\|UniProtKB:P11441	96..138		7/37 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810