DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ubi-p5E and NEDD8-MDP1

DIOPT Version :9

Sequence 1:NP_001284937.1 Gene:Ubi-p5E / 326237 FlyBaseID:FBgn0086558 Length:534 Species:Drosophila melanogaster
Sequence 2:NP_001186752.1 Gene:NEDD8-MDP1 / 100528064 HGNCID:39551 Length:193 Species:Homo sapiens


Alignment Length:198 Identity:62/198 - (31%)
Similarity:97/198 - (48%) Gaps:35/198 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDG----RTLSDYNI 61
            |.|.|||||||.|.:::||:|.:|.:|.::::||||||.|||||::|||: ||    |...|..:
Human     1 MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQI-DGTVRDRRGQDVRL 64

  Fly    62 QKESTLHLVLRLR-----GGMQIFVKTLTGKTITL------------EVEPSDTIENVKAKIQDK 109
            ..| ...::.||:     |........:.|....|            |:.|...|.:.: ::|.|
Human    65 YPE-VPEVLKRLQSLGVPGAAASRTSEIEGANQLLELFDLFRYFVHREIYPGSKITHFE-RLQQK 127

  Fly   110 EGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHL-----VLRLRGGMQIFVKTLTGK-TITLE 168
            .|||..|  :||..   ::.|.:.|.:....:.:|:     :..|..|::.|.|..||. ..:||
Human   128 TGIPFSQ--MIFFD---DERRNIVDVSKLGVTCIHIQNGMNLQTLSQGLETFAKAQTGPLRSSLE 187

  Fly   169 VEP 171
            ..|
Human   188 ESP 190

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ubi-p5ENP_001284937.1 Ubiquitin 1..76 CDD:176398 36/83 (43%)
UBQ 1..72 CDD:214563 34/74 (46%)
Ubiquitin 77..152 CDD:176398 17/91 (19%)
UBQ 77..148 CDD:214563 16/87 (18%)
Ubiquitin 153..228 CDD:176398 7/20 (35%)
UBQ 153..224 CDD:214563 7/20 (35%)
Ubiquitin 229..304 CDD:176398
UBQ 229..300 CDD:214563
Ubiquitin 305..380 CDD:176398
UBQ 305..376 CDD:214563
Ubiquitin 381..456 CDD:176398
UBQ 381..452 CDD:214563
Ubiquitin 457..532 CDD:176398
UBQ 457..528 CDD:214563
NEDD8-MDP1NP_001186752.1 UBQ 1..>51 CDD:294102 29/50 (58%)
UBQ 1..>50 CDD:214563 28/48 (58%)
Acid_PPase 51..177 CDD:289459 27/132 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5272
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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